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- W2033508117 abstract "The effect of leukocytes on the anti-Candida activity of neutrophils was examined. Murine neutrophils which were purified from casein-induced peritoneal cells inhibited the mycelial growth of Candida albicans. This anti-Candida activity of neutrophils was augmented by the addition of spleen cells prepared from mice pretreated with bacterial lipopolysaccharide 3 hr before, but not from non-treated mice. The population in the spleen cells, which enhanced the anti-Candida activity of neutrophils, was plastic-plate adherent, nylon-fiber columns adherent and anti-Mac-1 antigen-positive. These immunological profiles suggested that the enhancing cells are classified to splenic macrophages. Peritoneal-exudated macrophages from mice treated with lipopolysaccharide also augmented the anti-Candida activity of neutrophils. These results suggest that the anti-Candida activity of neutrophils may be upregulated by activated macrophages." @default.
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- W2033508117 date "1999-03-01" @default.
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- W2033508117 title "Effective Inhibition ofCandida albicansGrowth by the Combination of Murine Peritoneal Neutrophils and Activated Macrophages" @default.
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- W2033508117 doi "https://doi.org/10.1111/j.1348-0421.1999.tb02398.x" @default.
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