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• W2033526488 abstract "Relatively few studies have investigated pharmacological or behavioral treatment of smokeless tobacco (ST) users who do not have immediate quit plans. In this study, we compared a reduction treatment approach with an immediate cessation approach in a population of ST users who reported no immediate plans to quit. Subjects randomly assigned to the immediate cessation condition set a quit date soon after enrollment and were offered 2 weeks of nicotine patch therapy to help in their cessation efforts. Subjects assigned to the ST reduction group were provided with their choice of either 4 mg nicotine lozenge or ST brand switching to help them reduce their ST use or levels of nicotine exposure, respectively. Quit date was 6 weeks after the onset of treatment. Follow-up was at 12 weeks and 26 weeks postenrollment and 26 weeks postquit. Both 7-day point prevalence abstinence and prolonged abstinence rates following the quit date were significantly higher in the immediate cessation group versus the reduction group at 12 and 26 weeks (all p values ≤ .04) and for prolonged abstinence at 6 months postquit (p = .002). Significant reductions in ST use among nonquitters were observed for both groups (p < .0001) with no differences between groups. Our study demonstrated that immediate cessation with an established quit date resulted in greater cessation success than a gradual reduction approach among ST users who do not have an immediate quit plan but are motivated to quit." @default.
• W2033526488 created "2016-06-24" @default.
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• W2033526488 date "2012-01-04" @default.
• W2033526488 modified "2023-10-16" @default.
• W2033526488 title "Comparing an Immediate Cessation Versus Reduction Approach to Smokeless Tobacco Cessation" @default.
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• W2033526488 doi "https://doi.org/10.1093/ntr/ntr302" @default.
• W2033526488 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3530899" @default.
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• W2033526488 hasPublicationYear "2012" @default.
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