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- W2033528076 abstract "To investigate maternal cardiovascular function in pregnancies complicated by fetal growth restriction (FGR). Maternal echocardiography and 24 h ambulatory blood pressure monitoring were performed in normotensive pregnancies complicated by FGR (n = 12) and controls (n = 12). Maternal blood pressure and total vascular resistance were higher, and heart rate lower, in FGR pregnancies compared to controls. No significant differences between the two groups were observed for left atrial or left ventricular dimensions, nor for left ventricular geometry. Systolic function, as expressed by midwall fractional shortening, was lower in the FGR group. Diastolic function assessment by means of transmitral Doppler flow measurements revealed a significantly longer isovolumetric relaxation time in pregnancies with FGR (Table). In normotensive pregnancies complicated by FGR, as compared to controls, a number of alterations in maternal cardiovascular function can be observed by means of both echocardiography and ambulatory blood pressure monitoring, involving reduced diastolic and systolic function, higher blood pressure and reduced heart rate. The significance of these findings in the pathogenesis of uteroplacental insufficiency and growth restriction, and their possible role in the clinical management of these pregnancies, deserve further investigation." @default.
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- W2033528076 date "2007-09-21" @default.
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- W2033528076 title "OP01.03: Maternal cardiovascular function and ambulatory blood pressure monitoring in pregnancies complicated by fetal growth restriction" @default.
- W2033528076 doi "https://doi.org/10.1002/uog.4392" @default.
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