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- W2033528259 abstract "Abstract The experience of the Istituto Nazionale Tumori of Milan of 143 patients who underwent extended surgery for cancer of the stomach from 1965 to 1980 is reviewed. They represent 16·3 per cent of the patients who underwent curative surgery. The operative mortality rate was 15·4 per cent but this significantly decreased in recent years to 8per cent and the morbidity rate to 17·5 percent. The overall 5-year survival rate was 19 per cent. Survival was analysed according to tumour penetration (pT) and nodal status (N). It was found that patients without tumour penetration of adjacent structures and nodal involvement (pT3N−) had a better 5-year survival rate (21 per cent) than patients with nodal involvement (pT3N+) (2 per cent). Patients with tumour penetration of adjacent structures and without nodal involvement (pT4N−) had a better 5-year survival rate (29 per cent) than patients with nodal involvement (pT4N+) (5 per cent). These differences were significant on log rank test (P < 0·000001 and P < 0·001 respectively) and suggest that nodal status is a stronger prognostic variable than pT level. The role of extended surgery is discussed from the viewpoint of the oncological surgeon who has to weigh up the difficulty of a preoperative diagnosis of tumour infiltration of adjacent structures (predictive positive value 0·39), with the operative mortality rate of at least 8per cent and long-term results which are strongly affected by the nodal status." @default.
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- W2033528259 date "1990-01-01" @default.
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- W2033528259 title "Early and late results of extended surgery for cancer of the stomach" @default.
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- W2033528259 doi "https://doi.org/10.1002/bjs.1800770119" @default.
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