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- W2033541266 endingPage "1780" @default.
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- W2033541266 abstract "The aim of present study is to evaluate the effects of Garcinia cambogia on the mRNA levels of the various genes involved in adipogenesis, as well as on body weight gain, visceral fat accumulation, and other biochemical markers of obesity in obesity-prone C57BL/6J mice. Consumption of the Garcinia cambogia extract effectively lowered the body weight gain, visceral fat accumulation, blood and hepatic lipid concentrations, and plasma insulin and leptin levels in a high-fat diet (HFD)-induced obesity mouse model. The Garcinia cambogia extract reversed the HFD-induced changes in the expression pattern of such epididymal adipose tissue genes as adipocyte protein aP2 (aP2), sterol regulatory element-binding factor 1c (SREBP1c), peroxisome proliferator-activated receptor γ2 (PPARγ2), and CCAT/enhancer-binding protein α (C/EBPα). These findings suggest that the Garcinia cambogia extract ameliorated HFD-induced obesity, probably by modulating multiple genes associated with adipogenesis, such as aP2, SREBP1c, PPARγ2, and C/EBPα in the visceral fat tissue of mice." @default.
- W2033541266 created "2016-06-24" @default.
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- W2033541266 date "2008-07-23" @default.
- W2033541266 modified "2023-10-16" @default.
- W2033541266 title "<i>Garcinia cambogia</i>Extract Ameliorates Visceral Adiposity in C57BL/6J Mice Fed on a High-Fat Diet" @default.
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- W2033541266 doi "https://doi.org/10.1271/bbb.80072" @default.
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