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- W2033616785 abstract "Abstract Chalcone derivatives have been synthesized by the reaction of 3-acetyl-2,5-dimethylthiophene with corresponding active aldehyde in ethanolic NaOH in microwave oven. The structure of these compounds was established by elemental analysis, IR, 1H NMR, 13C NMR and EI-MS spectral analysis. The anti-bacterial activity of these compounds were first tested in vitro by the disk diffusion assay against two Gram-positive and two Gram-negative bacteria, and then the minimum inhibitory concentration (MIC) was determined with the reference of standard drug Chloramphenicol. The results showed that compound 8 is a better inhibitor of both types of the bacteria (Gram-positive and Gram-negative) as compared to chloramphenicol." @default.
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- W2033616785 date "2017-05-01" @default.
- W2033616785 modified "2023-10-16" @default.
- W2033616785 title "Green synthesis, characterization and biological evaluation of novel chalcones as anti bacterial agents" @default.
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- W2033616785 doi "https://doi.org/10.1016/j.arabjc.2013.11.018" @default.
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