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- W2033623237 abstract "El carcinoma hepatocelular (CHC) constituye la cuarta causa de mortalidad por cáncer en el mundo. El CHC puede presentarse sobre hígados sanos, pero en más del 80% asienta sobre cirrosis previa. Las hepatitis crónicas por virus B y C y la cirrosis alcohólica son los factores etiológicos de CHC más frecuentes. La forma histológica de mayor prevalencia es el HCC de origen epitelial tipo adenocarcinoma. Actualmente están desarrollados programas de detección precoz en pacientes con factores de riesgo para CHC con el objetivo de detectar la enfermedad en fases precoces y con posibilidades de resección. Las posibilidades de tratamiento del CHC son variadas (resección, terapias locales ablativas, trasplante hepático, radioterapia, quimioterapia y nuevos agentes como sorafenib) y vienen determinadas por el estadio y la situación general del paciente. Los carcinomas del tracto biliar comprenden aquéllos originados en la vesícula y en la vía biliar intra y extrahepática. Son tumores poco frecuentes y, en general, de mal pronóstico. Su tratamiento es complejo y requieren un manejo multidisciplinar. Hepatocellular carcinoma (HCC) represents the fourth most common cause of death from cancer. The etiologic agents responsible for the majority of HCC are the infections with hepatitis B and C viruses and ethanol abuse. Adenocarcinoma is the most frequent hystologic type. Surveillance is performed with provided evidence-base recommendations for identification of patients at risk. The clinical management choices for HCC are complex because of the numerous options that exist for treatment (excision, local ablation strategies, liver transplantation, radiation therapy, regional and systemic chemotherapy and novel agents as sorafenib) and the underlying liver disease that affects the majority of HCC patients. The cancer of the biliary tract includes the gallbladder and intrahepatic and extrahepatic bile ducts tumors. These cancers are, in general, rare and with overall poor prognosis. The management of patients with biliary tract cancer is complex and a dedicated, multidisciplinary team is necessary." @default.
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- W2033623237 date "2013-02-01" @default.
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- W2033623237 title "Cáncer de hígado y vía biliar" @default.
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- W2033623237 doi "https://doi.org/10.1016/s0304-5412(13)70490-6" @default.
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