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• W2033681330 abstract "It requires only a very cursory acquaintance with the literature of radiobiology to appreciate that the production of cancer in the higher animals is one of the more important and well-established actions of radiation. Cancer, in fact, follows radiation under the required range of conditions with such regularity and in such a wide range of species that one may think of radiation as the most universal carcinogen of all, and one may expect that the study of this process will reveal important facts about both the nature of radiation effects and the nature of the neoplastic process. In this essay, no attempt will be made to cover this subject in detail. This has been done recently in several reviews, including two by the writer (1, 2), and most recently and compendiously by Furth and Lorenz (3). The purpose of this paper is to consider some of the principles so far established (or which need to be established), not only in the light of basic biophysics, but in relation to such more practical matters as the limits of our knowledge in establishing industrial or world-wide permissible levels of radiation exposure. It is always a painful matter for a conscientious investigator to undertake the obligation of seeking out inevitably inadequate data for the purpose of establishing such permissible levels-with the realization that such levels may if too high be unsafe, whereas if too low they may raise the cost of, or delay, nuclear development. In any case it is clear that cancer is one of the most important limiting factors in determining safe exposure conditions and that the evaluation of these from experimental data requires the best possible understanding of some basic questions. We shall proceed by asking certain questions and looking at the state of knowledge in each area." @default.
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• W2033681330 date "1955-11-01" @default.
• W2033681330 modified "2023-09-23" @default.
• W2033681330 title "Radiation as a Carcinogenic Agent" @default.
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