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- W2033714511 abstract "The mutagenicities of aniline, o-toluidine and yellow OB were demonstrated only in the presence of the β-carboline compound, norharman. The effect of norharman increased linearly with increase in the amount of S-9. The mutagenicity of 4-dimethylaminoazobenzene was greatly enhanced by the presence of norharman, and again dose-dependency on the amount of S-9 was observed. In the presence of a large amount of S-9, norharman caused several fold enhancement of the mutagenicities of N-2-fluorenylacetamide, benzo(a)-pyrene, and 1,4-dimethyl-3-amino-5H-pyrido(4,3b) indole, isolated from a tryptophan pyrolysate. However, norharman suppressed the mutagenicities of these compounds in the presence of a small amount of S-9. The mutagenicity of kaempferol, a flavonoid, was inhibited by norharman with either a large or small amount of S-9." @default.
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- W2033714511 date "1978-07-01" @default.
- W2033714511 modified "2023-09-25" @default.
- W2033714511 title "Differences in effects of norharman with various classes of chemical mutagens and amounts of S-9" @default.
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- W2033714511 doi "https://doi.org/10.1016/0006-291x(78)91000-8" @default.
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