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- W2033716113 abstract "Nonisotopic in situ hybridization has been used to investigate the role of Epstein-Barr virus (EBV) in the aetiology of pediatric Hodgkin's disease. Sections from 24 cases arising in children under the age of 15 years were hybridised with digoxigenin-labelled probes for both EBV and cytomegalovirus, and reactive sites were identified by a sensitive three-layer immunoperoxidase technique. EBV was identified in Reed-Sternberg and mononuclear Hodgkin's cells in five samples (21%). No samples were positive when the cytomegalovirus probe was employed. The specific identification of EBV in the malignant cells of Hodgkin's disease arising in children lends further support for a role of EBV in the aetiology of this disorder." @default.
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- W2033716113 date "1993-01-01" @default.
- W2033716113 modified "2023-10-01" @default.
- W2033716113 title "Detection of Epstein-Barr virus in Reed-Sternberg cells of Hodgkin's disease arising in children" @default.
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- W2033716113 doi "https://doi.org/10.1002/mpo.2950210105" @default.
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