FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033729168> ?p ?o ?g. }

• W2033729168 endingPage "236" @default.
• W2033729168 startingPage "231" @default.
• W2033729168 abstract "A new aptamer biosensor was presented for the detection of thrombin in this work, which was based on fluorescence polarization (FP) using silica nanoparticles as enhancement probe. The silica nanoparticles covered by streptavidin were tagged with a thrombin aptamer (5'-biotin-GGTTGGTGTGGTTGG-3'), which was bound to the surface of silica nanoparticle through the specific interaction between streptavidin and biotin. In the presence of thrombin, it induced the aptamer to form quadruplex structure. When the other thrombin aptamer labeled with fluorescein (5'-FAM-AGTCCGTGGTAGGGCAGGTTGGGGTGACT-3') was added to the above system, a sandwich structure can form at the surface of silica nanoparticles. The fluorescence polarization was therefore enhanced and quantification between fluorescence polarization signal and concentration of thrombin was built. The sensor provided a linear range from 0.6 to 100 nM for thrombin with a detection limit of 0.20 nM (3.29SB/m, according to the recent recommendation of IUPAC) in a homogeneous media. The same linear range was obtained in spiked human serum samples with a slightly higher detection limit (0.26 nM), demonstrating high anti-interference of the sensor in a complex biological sample matrix. And the sensor can be used to monitor spiked concentration of thrombin level in real human plasma with satisfactory results obtained." @default.
• W2033729168 created "2016-06-24" @default.
• W2033729168 creator A5011502894 @default.
• W2033729168 creator A5015976220 @default.
• W2033729168 creator A5039911465 @default.
• W2033729168 creator A5040588331 @default.
• W2033729168 creator A5044564570 @default.
• W2033729168 creator A5047886846 @default.
• W2033729168 creator A5055944783 @default.
• W2033729168 creator A5073216396 @default.
• W2033729168 creator A5076143374 @default.
• W2033729168 creator A5085340020 @default.
• W2033729168 date "2014-06-01" @default.
• W2033729168 modified "2023-10-16" @default.
• W2033729168 title "A convenient sandwich assay of thrombin in biological media using nanoparticle-enhanced fluorescence polarization" @default.
• W2033729168 cites W154792339 @default.
• W2033729168 cites W1552647544 @default.
• W2033729168 cites W1964466080 @default.
• W2033729168 cites W1964858690 @default.
• W2033729168 cites W1967345725 @default.
• W2033729168 cites W1969013851 @default.
• W2033729168 cites W1978754949 @default.
• W2033729168 cites W1986585549 @default.
• W2033729168 cites W1993176979 @default.
• W2033729168 cites W2006402809 @default.
• W2033729168 cites W2006480909 @default.
• W2033729168 cites W2013243779 @default.
• W2033729168 cites W2014861260 @default.
• W2033729168 cites W2016697417 @default.
• W2033729168 cites W2016754833 @default.
• W2033729168 cites W2027503402 @default.
• W2033729168 cites W2029303494 @default.
• W2033729168 cites W2029812620 @default.
• W2033729168 cites W2035608404 @default.
• W2033729168 cites W2037339361 @default.
• W2033729168 cites W2038539241 @default.
• W2033729168 cites W2041859669 @default.
• W2033729168 cites W2045051369 @default.
• W2033729168 cites W2046546023 @default.
• W2033729168 cites W2055721693 @default.
• W2033729168 cites W2056004069 @default.
• W2033729168 cites W2070061959 @default.
• W2033729168 cites W2075051940 @default.
• W2033729168 cites W2075331103 @default.
• W2033729168 cites W2077028663 @default.
• W2033729168 cites W2079321730 @default.
• W2033729168 cites W2079970102 @default.
• W2033729168 cites W2080624874 @default.
• W2033729168 cites W2082572892 @default.
• W2033729168 cites W2086047273 @default.
• W2033729168 cites W2104525153 @default.
• W2033729168 cites W2119009173 @default.
• W2033729168 cites W2128590183 @default.
• W2033729168 cites W2141001024 @default.
• W2033729168 cites W2319305623 @default.
• W2033729168 cites W2322695106 @default.
• W2033729168 cites W2324821261 @default.
• W2033729168 cites W2616187906 @default.
• W2033729168 doi "https://doi.org/10.1016/j.bios.2014.01.021" @default.
• W2033729168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24508546" @default.
• W2033729168 hasPublicationYear "2014" @default.
• W2033729168 type Work @default.
• W2033729168 sameAs 2033729168 @default.
• W2033729168 citedByCount "60" @default.
• W2033729168 countsByYear W20337291682014 @default.
• W2033729168 countsByYear W20337291682015 @default.
• W2033729168 countsByYear W20337291682016 @default.
• W2033729168 countsByYear W20337291682017 @default.
• W2033729168 countsByYear W20337291682018 @default.
• W2033729168 countsByYear W20337291682019 @default.
• W2033729168 countsByYear W20337291682020 @default.
• W2033729168 countsByYear W20337291682021 @default.
• W2033729168 countsByYear W20337291682022 @default.
• W2033729168 crossrefType "journal-article" @default.
• W2033729168 hasAuthorship W2033729168A5011502894 @default.
• W2033729168 hasAuthorship W2033729168A5015976220 @default.
• W2033729168 hasAuthorship W2033729168A5039911465 @default.
• W2033729168 hasAuthorship W2033729168A5040588331 @default.
• W2033729168 hasAuthorship W2033729168A5044564570 @default.
• W2033729168 hasAuthorship W2033729168A5047886846 @default.
• W2033729168 hasAuthorship W2033729168A5055944783 @default.
• W2033729168 hasAuthorship W2033729168A5073216396 @default.
• W2033729168 hasAuthorship W2033729168A5076143374 @default.
• W2033729168 hasAuthorship W2033729168A5085340020 @default.
• W2033729168 hasConcept C10349863 @default.
• W2033729168 hasConcept C111357860 @default.
• W2033729168 hasConcept C113196181 @default.
• W2033729168 hasConcept C119128265 @default.
• W2033729168 hasConcept C120665830 @default.
• W2033729168 hasConcept C121332964 @default.
• W2033729168 hasConcept C128972844 @default.
• W2033729168 hasConcept C153911025 @default.
• W2033729168 hasConcept C155672457 @default.
• W2033729168 hasConcept C160756335 @default.
• W2033729168 hasConcept C171250308 @default.
• W2033729168 hasConcept C185592680 @default.
• W2033729168 hasConcept C192562407 @default.
• W2033729168 hasConcept C203014093 @default.

• next