Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033735401> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2033735401 endingPage "2432" @default.
- W2033735401 startingPage "2425" @default.
- W2033735401 abstract "The yeast gene PBS2 encodes a presumed protein kinase. The gene is essential for manifestation of resistance to the antibiotic polymyxin B. Deletion of PBS2 enables a ras2-530 null mutant to grow on nonfermentable carbon sources; overexpression of PBS2+ enhances viability of a RAS2Val19 mutant. Overexpression of PBS2+ also diminishes cellular response to mating pheromone MF alpha. These results suggest that the PBS2 and RAS2 genes affect a common pathway that may communicate with the pheromone response pathway. In addition, disruption of PBS2 renders cells sensitive to high osmolarity: exposure to 0.9 M-NaCl causes growth arrest, appearance of bizarre morphological forms, and eventual death. A mutation suppressing pbs2 deletion has been found. That mutation restores full polymyxin B resistance but only partially corrects the osmotic sensitivity defect. These observations indicate that PBS2 is involved in diverse physiological pathways in yeast." @default.
- W2033735401 created "2016-06-24" @default.
- W2033735401 creator A5047468774 @default.
- W2033735401 date "1992-11-01" @default.
- W2033735401 modified "2023-10-16" @default.
- W2033735401 title "PBS2, a yeast gene encoding a putative protein kinase, interacts with the RAS2 pathway and affects osmotic sensitivity of Saccharomyces cerevisiae" @default.
- W2033735401 cites W1500370116 @default.
- W2033735401 cites W1526043578 @default.
- W2033735401 cites W1530468540 @default.
- W2033735401 cites W1760166978 @default.
- W2033735401 cites W1968948620 @default.
- W2033735401 cites W1988579556 @default.
- W2033735401 cites W1995217068 @default.
- W2033735401 cites W1998407663 @default.
- W2033735401 cites W2003457510 @default.
- W2033735401 cites W2008014792 @default.
- W2033735401 cites W2020257412 @default.
- W2033735401 cites W2034831369 @default.
- W2033735401 cites W2046508015 @default.
- W2033735401 cites W2062963816 @default.
- W2033735401 cites W2064494501 @default.
- W2033735401 cites W2066504922 @default.
- W2033735401 cites W2076300921 @default.
- W2033735401 cites W2078378775 @default.
- W2033735401 cites W2084310148 @default.
- W2033735401 cites W2094832727 @default.
- W2033735401 cites W2101882623 @default.
- W2033735401 cites W2107737466 @default.
- W2033735401 cites W2109093658 @default.
- W2033735401 cites W2126559707 @default.
- W2033735401 cites W2130667022 @default.
- W2033735401 cites W2162382740 @default.
- W2033735401 cites W2169973516 @default.
- W2033735401 cites W2175068438 @default.
- W2033735401 cites W2413556016 @default.
- W2033735401 doi "https://doi.org/10.1099/00221287-138-11-2425" @default.
- W2033735401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1479360" @default.
- W2033735401 hasPublicationYear "1992" @default.
- W2033735401 type Work @default.
- W2033735401 sameAs 2033735401 @default.
- W2033735401 citedByCount "85" @default.
- W2033735401 countsByYear W20337354012012 @default.
- W2033735401 countsByYear W20337354012013 @default.
- W2033735401 countsByYear W20337354012014 @default.
- W2033735401 countsByYear W20337354012015 @default.
- W2033735401 countsByYear W20337354012016 @default.
- W2033735401 countsByYear W20337354012018 @default.
- W2033735401 countsByYear W20337354012019 @default.
- W2033735401 countsByYear W20337354012023 @default.
- W2033735401 crossrefType "journal-article" @default.
- W2033735401 hasAuthorship W2033735401A5047468774 @default.
- W2033735401 hasBestOaLocation W20337354011 @default.
- W2033735401 hasConcept C104317684 @default.
- W2033735401 hasConcept C143065580 @default.
- W2033735401 hasConcept C184235292 @default.
- W2033735401 hasConcept C2777576037 @default.
- W2033735401 hasConcept C2779222958 @default.
- W2033735401 hasConcept C2780026444 @default.
- W2033735401 hasConcept C2910135453 @default.
- W2033735401 hasConcept C501593827 @default.
- W2033735401 hasConcept C501734568 @default.
- W2033735401 hasConcept C54355233 @default.
- W2033735401 hasConcept C86803240 @default.
- W2033735401 hasConcept C89423630 @default.
- W2033735401 hasConcept C95444343 @default.
- W2033735401 hasConceptScore W2033735401C104317684 @default.
- W2033735401 hasConceptScore W2033735401C143065580 @default.
- W2033735401 hasConceptScore W2033735401C184235292 @default.
- W2033735401 hasConceptScore W2033735401C2777576037 @default.
- W2033735401 hasConceptScore W2033735401C2779222958 @default.
- W2033735401 hasConceptScore W2033735401C2780026444 @default.
- W2033735401 hasConceptScore W2033735401C2910135453 @default.
- W2033735401 hasConceptScore W2033735401C501593827 @default.
- W2033735401 hasConceptScore W2033735401C501734568 @default.
- W2033735401 hasConceptScore W2033735401C54355233 @default.
- W2033735401 hasConceptScore W2033735401C86803240 @default.
- W2033735401 hasConceptScore W2033735401C89423630 @default.
- W2033735401 hasConceptScore W2033735401C95444343 @default.
- W2033735401 hasIssue "11" @default.
- W2033735401 hasLocation W20337354011 @default.
- W2033735401 hasLocation W20337354012 @default.
- W2033735401 hasOpenAccess W2033735401 @default.
- W2033735401 hasPrimaryLocation W20337354011 @default.
- W2033735401 hasRelatedWork W1968643238 @default.
- W2033735401 hasRelatedWork W1975929799 @default.
- W2033735401 hasRelatedWork W1979310538 @default.
- W2033735401 hasRelatedWork W2014319751 @default.
- W2033735401 hasRelatedWork W2021674453 @default.
- W2033735401 hasRelatedWork W2072731694 @default.
- W2033735401 hasRelatedWork W2094041192 @default.
- W2033735401 hasRelatedWork W2409355196 @default.
- W2033735401 hasRelatedWork W3120238434 @default.
- W2033735401 hasRelatedWork W4248869635 @default.
- W2033735401 hasVolume "138" @default.
- W2033735401 isParatext "false" @default.
- W2033735401 isRetracted "false" @default.
- W2033735401 magId "2033735401" @default.
- W2033735401 workType "article" @default.