Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033819319> ?p ?o ?g. }
- W2033819319 endingPage "1206" @default.
- W2033819319 startingPage "1198" @default.
- W2033819319 abstract "There is an increasing interest in identifying potent cancer-preventive and therapeutic agents against breast cancer. A great number of reports have in recent years dealt with anticancer characteristics of Semecarpus anacardium nut extract (SA). The majority of these studies has been targeted on the protective effect rendered to the living system rather than the preventive effect on cancer cells. SA was tested for its inhibitory effect on human breast cancer cells (T47D). Cytotoxicity analyses suggested that these cells had become apoptotic. SA was discovered to induce rapid Ca(2+) mobilization from intracellular stores of T47D cell line, and its cytotoxicity against T47D was well correlated with altered mitochondrial transmembrane potential. At the molecular level, these changes are accompanied by decrease in bcl(2) and increase in bax, cytochrome c, caspases and PARP cleavage, and ultimately by internucleosomal DNA fragmentation. Taken together, our results provide unprecedented evidence that SA triggers apoptotic signals in T47D cells." @default.
- W2033819319 created "2016-06-24" @default.
- W2033819319 creator A5012649622 @default.
- W2033819319 creator A5036175177 @default.
- W2033819319 creator A5078902422 @default.
- W2033819319 date "2007-10-01" @default.
- W2033819319 modified "2023-10-13" @default.
- W2033819319 title "Apoptotic effect of Semecarpus anacardium nut extract on T47D breast cancer cell line" @default.
- W2033819319 cites W1276370372 @default.
- W2033819319 cites W1500228509 @default.
- W2033819319 cites W1506642042 @default.
- W2033819319 cites W1599277155 @default.
- W2033819319 cites W1607531254 @default.
- W2033819319 cites W1665071864 @default.
- W2033819319 cites W1830337001 @default.
- W2033819319 cites W1845459216 @default.
- W2033819319 cites W1892554314 @default.
- W2033819319 cites W1959879209 @default.
- W2033819319 cites W1963791094 @default.
- W2033819319 cites W1967012492 @default.
- W2033819319 cites W1980462656 @default.
- W2033819319 cites W1985260283 @default.
- W2033819319 cites W1991102255 @default.
- W2033819319 cites W1992069532 @default.
- W2033819319 cites W1997170151 @default.
- W2033819319 cites W2002407199 @default.
- W2033819319 cites W2006022885 @default.
- W2033819319 cites W2010298858 @default.
- W2033819319 cites W2014032809 @default.
- W2033819319 cites W2019693597 @default.
- W2033819319 cites W2022015605 @default.
- W2033819319 cites W2059104701 @default.
- W2033819319 cites W2060270769 @default.
- W2033819319 cites W2064866491 @default.
- W2033819319 cites W2070862399 @default.
- W2033819319 cites W2078899739 @default.
- W2033819319 cites W2080713254 @default.
- W2033819319 cites W2084060660 @default.
- W2033819319 cites W2086050696 @default.
- W2033819319 cites W2092326349 @default.
- W2033819319 cites W2095491456 @default.
- W2033819319 cites W2097906753 @default.
- W2033819319 cites W2101969083 @default.
- W2033819319 cites W2113999599 @default.
- W2033819319 cites W2117894872 @default.
- W2033819319 cites W2119683782 @default.
- W2033819319 cites W2123489616 @default.
- W2033819319 cites W2125961906 @default.
- W2033819319 cites W2131878763 @default.
- W2033819319 cites W2141000153 @default.
- W2033819319 cites W2141894346 @default.
- W2033819319 cites W2147357406 @default.
- W2033819319 cites W2149429457 @default.
- W2033819319 cites W2150675831 @default.
- W2033819319 cites W2168372891 @default.
- W2033819319 cites W243572519 @default.
- W2033819319 cites W2439883951 @default.
- W2033819319 doi "https://doi.org/10.1016/j.cellbi.2007.04.004" @default.
- W2033819319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17572113" @default.
- W2033819319 hasPublicationYear "2007" @default.
- W2033819319 type Work @default.
- W2033819319 sameAs 2033819319 @default.
- W2033819319 citedByCount "29" @default.
- W2033819319 countsByYear W20338193192012 @default.
- W2033819319 countsByYear W20338193192013 @default.
- W2033819319 countsByYear W20338193192014 @default.
- W2033819319 countsByYear W20338193192015 @default.
- W2033819319 countsByYear W20338193192016 @default.
- W2033819319 countsByYear W20338193192017 @default.
- W2033819319 countsByYear W20338193192018 @default.
- W2033819319 countsByYear W20338193192019 @default.
- W2033819319 countsByYear W20338193192020 @default.
- W2033819319 countsByYear W20338193192021 @default.
- W2033819319 countsByYear W20338193192022 @default.
- W2033819319 countsByYear W20338193192023 @default.
- W2033819319 crossrefType "journal-article" @default.
- W2033819319 hasAuthorship W2033819319A5012649622 @default.
- W2033819319 hasAuthorship W2033819319A5036175177 @default.
- W2033819319 hasAuthorship W2033819319A5078902422 @default.
- W2033819319 hasConcept C109316439 @default.
- W2033819319 hasConcept C121608353 @default.
- W2033819319 hasConcept C182979987 @default.
- W2033819319 hasConcept C185592680 @default.
- W2033819319 hasConcept C190283241 @default.
- W2033819319 hasConcept C202751555 @default.
- W2033819319 hasConcept C29311851 @default.
- W2033819319 hasConcept C31573885 @default.
- W2033819319 hasConcept C43759708 @default.
- W2033819319 hasConcept C502942594 @default.
- W2033819319 hasConcept C54355233 @default.
- W2033819319 hasConcept C552990157 @default.
- W2033819319 hasConcept C55493867 @default.
- W2033819319 hasConcept C556039675 @default.
- W2033819319 hasConcept C71924100 @default.
- W2033819319 hasConcept C82381507 @default.
- W2033819319 hasConcept C86803240 @default.
- W2033819319 hasConcept C96232424 @default.
- W2033819319 hasConcept C98274493 @default.