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• W2033825702 abstract "LEARNING OUTCOME: To measure adherence of subjects prescribed a low protein diet using an individualized approach and frequent counseling. Individuals with early stage chronic renal insufficiency (CRI) may benefit from a low protein diet. We investigated the effects of exercise in protein-restricted subjects with CRI aged 48–79 y (mean=64±11 y) who were recruited from the greater Boston area who had a mean baseline serum creatinine of 2.9±1.0mg/dl and mean GFR of 32.9±27.3ml/min. Six subjects were prescribed a low protein diet (0.6g/kg adjusted body wt/d); the mean adherence period was 4±1 wks. Subjects were seen individually by a research dietitian 2x/wk for about 30–60 min/visit. Food records (FR) were recorded by patients 6 d/wk and analyzed using Nutritionist IV version 4.0. Twenty-four hour urine was collected 2x/wk to measure urine urea nitrogen (UUN) by the enzymatic method. FR and UUN showed a significant decrease in protein intake at the start of adherence period. Mean FR and UUN for protein intake were 82.78±26.14g/d (0.98 ± 0.13g/kg body wt/d) and 74.0±36.0g/d (0.86± 0.31g/kg body wt/d) respectively. At the end of adherence period, approximately 4 wks later, mean protein intake by FR was 39.89±11.49g/d (0.5±0.1g/kg body wt/d) and by UUN mean protein intake was 52.0±11.01g/d (0.64±0.05g/kg body wt/d); a decrease in habitual protein intake of 49% and 25% respectively as estimated from FR and UUN. Subjects underreported their food intake when total calories calculated from food records were compared to total energy expenditure from indirect calorimetry using a physical activity factor of 1.2. Degree of underreporting was most apparent in the subject with the lowest instrumental activities of daily living score. Subjects newly prescribed a low protein diet were able to reach the goal of 0.6 g protein/kg utilizing these techniques. Although a low protein diet may be desirable in early stage CRI, clinicians may experience difficulty with adherence due to lack of counseling time and frequent monitoring." @default.
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• W2033825702 date "1997-09-01" @default.
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• W2033825702 title "Food Records Vs Urine Urea Nitrogen in Assessing Adherence to a Low- Protein Diet in Early Stage Chronic Renal Insufficiency." @default.
• W2033825702 doi "https://doi.org/10.1016/s0002-8223(97)00422-7" @default.
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