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• W2033853838 abstract "Background and Purpose: Inguinofemoral lymphadenectomy (IFLA) is a standard procedure for cancer of the external genitalia. Open lymphadenectomy (O-IFLA) exhibits complication rates of more than 50%. We are demonstrating our extended experience with a modified endoscopic approach (E-IFLA) for groin lymphadenectomy. Patients and Methods: Patients with nonpalpable as well as those with palpable nodes who had IFLA were identified. O-IFLA comprised both superficial and deep inguinal lymph node dissection. E-IFLA was performed using a three-trocar approach in the same field. We used a reduced CO2-pressure of <5 mm Hg. A suction drain was always placed. Perioperative data and postoperative outcomes were systematically assessed followed by statistical analysis. Results: We performed 62 IFLAs in 42 patients. Twenty-eight procedures were completed endoscopically. Follow-up was 55.8 months (2–87 mos). Mean operative time for O-IFLA was 101.7 minutes (38–195 min), being shorter than for E-IFLA (136.3 min, 87–186 min), P<0.001. Both groups are comparable regarding the number of nodes (O-IFLA 7.2, 2–16 vs E-IFLA 7.1, 4–13) as well as with regard to the number of positive nodes (O-IFLA 1.8 vs E-IFLA 1.6). Secondary wound healing and leg edema were extremely rare events (1/28) after E-IFLA. The overall complication rate was 7.1%. Complications appeared in 55.3% of the O-IFLA-cases. There were no problems related to CO2 insufflation. Local recurrence rates were identical in both groups. Conclusions: O-IFLA and E-IFLA are efficient with respect to oncologic safety. E-IFLA is technically more challenging. E-IFLA can avoid secondary wound healing and lymphatic complications. E-IFLA is a safe procedure while a reduction of CO2 pressures optimizes the safety profile. Because cancer control rates remained equivalent during an extended follow-up, oncologic durability could be confirmed." @default.
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• W2033853838 date "2013-04-01" @default.
• W2033853838 modified "2023-10-02" @default.
• W2033853838 title "Endoscopic Inguinofemoral Lymphadenectomy—Extended Follow-up" @default.
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• W2033853838 doi "https://doi.org/10.1089/end.2012.0489" @default.
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