Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033907568> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2033907568 endingPage "398" @default.
- W2033907568 startingPage "394" @default.
- W2033907568 abstract "The peptide N-Boc-L-Phe-dehydro-Abu-NH-CH3 was synthesized by the usual workup procedure. The crystals grown from methanol at 4 degrees C belong to the space group P2(1)2(1)2(1) with a = 7.589(2), b = 13.690(4), c = 21.897(6) A, Z = 4 and dc = 1.149(5) g cm-3 for C19H29N3O5.CH3OH. The peptide crystals were highly sensitive to radiation. The final agreement factor R was 0.055 for 1109 observed reflections (I > or = 2 sigma) with data extending to a 2 theta value of 103 degrees. The methanol oxygen atom is split into two occupancies. Both sites are involved in identical hydrogen bonding. As a result of substitution of a dehydro-Abu residue at the (i + 2) position the peptide adopts an ideal beta-turn II' conformation with torsion angles of corner residues as phi 1 = 63(1) degrees, psi 1 = -127(1) degrees, phi 2 = -66(1) degrees and psi 2 = -10(1) degrees, and an intramolecular hydrogen bond N-H...O of length 3.01(1) A. This shows that the conformational constraints produced by dehydro-Abu are similar in nature to but different in magnitude than those produced by dehydro-Phe and dehydro-Leu. The methanol-peptide interactions show characteristic features of multiple hydrogen-bond formations involving polar sites of participating peptide and methanol molecules. The packing of the molecules in the unit cell is stabilized by interactions through methanol molecules with the help of several hydrogen bonds." @default.
- W2033907568 created "2016-06-24" @default.
- W2033907568 creator A5036938163 @default.
- W2033907568 creator A5080146462 @default.
- W2033907568 date "2009-01-12" @default.
- W2033907568 modified "2023-09-25" @default.
- W2033907568 title "Molecular design of peptides" @default.
- W2033907568 cites W1986094359 @default.
- W2033907568 cites W2040539480 @default.
- W2033907568 cites W2042049133 @default.
- W2033907568 cites W2049850818 @default.
- W2033907568 cites W2055524664 @default.
- W2033907568 cites W2064280677 @default.
- W2033907568 cites W2066946402 @default.
- W2033907568 cites W2073614125 @default.
- W2033907568 cites W2075321603 @default.
- W2033907568 cites W2079964660 @default.
- W2033907568 cites W2089447294 @default.
- W2033907568 cites W2120560532 @default.
- W2033907568 cites W2127643291 @default.
- W2033907568 cites W2137398975 @default.
- W2033907568 cites W2319924636 @default.
- W2033907568 cites W2322521790 @default.
- W2033907568 cites W284452739 @default.
- W2033907568 cites W4246427018 @default.
- W2033907568 doi "https://doi.org/10.1111/j.1399-3011.1993.tb00455.x" @default.
- W2033907568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8496020" @default.
- W2033907568 hasPublicationYear "2009" @default.
- W2033907568 type Work @default.
- W2033907568 sameAs 2033907568 @default.
- W2033907568 citedByCount "11" @default.
- W2033907568 crossrefType "journal-article" @default.
- W2033907568 hasAuthorship W2033907568A5036938163 @default.
- W2033907568 hasAuthorship W2033907568A5080146462 @default.
- W2033907568 hasConcept C112887158 @default.
- W2033907568 hasConcept C178790620 @default.
- W2033907568 hasConcept C185592680 @default.
- W2033907568 hasConcept C2779281246 @default.
- W2033907568 hasConcept C2779607525 @default.
- W2033907568 hasConcept C2781338088 @default.
- W2033907568 hasConcept C32909587 @default.
- W2033907568 hasConcept C55493867 @default.
- W2033907568 hasConcept C71240020 @default.
- W2033907568 hasConcept C75079739 @default.
- W2033907568 hasConcept C8010536 @default.
- W2033907568 hasConceptScore W2033907568C112887158 @default.
- W2033907568 hasConceptScore W2033907568C178790620 @default.
- W2033907568 hasConceptScore W2033907568C185592680 @default.
- W2033907568 hasConceptScore W2033907568C2779281246 @default.
- W2033907568 hasConceptScore W2033907568C2779607525 @default.
- W2033907568 hasConceptScore W2033907568C2781338088 @default.
- W2033907568 hasConceptScore W2033907568C32909587 @default.
- W2033907568 hasConceptScore W2033907568C55493867 @default.
- W2033907568 hasConceptScore W2033907568C71240020 @default.
- W2033907568 hasConceptScore W2033907568C75079739 @default.
- W2033907568 hasConceptScore W2033907568C8010536 @default.
- W2033907568 hasIssue "4" @default.
- W2033907568 hasLocation W20339075681 @default.
- W2033907568 hasLocation W20339075682 @default.
- W2033907568 hasOpenAccess W2033907568 @default.
- W2033907568 hasPrimaryLocation W20339075681 @default.
- W2033907568 hasRelatedWork W1982460861 @default.
- W2033907568 hasRelatedWork W2006252551 @default.
- W2033907568 hasRelatedWork W2024080746 @default.
- W2033907568 hasRelatedWork W2061552628 @default.
- W2033907568 hasRelatedWork W2081734998 @default.
- W2033907568 hasRelatedWork W2092833964 @default.
- W2033907568 hasRelatedWork W2094541203 @default.
- W2033907568 hasRelatedWork W2606548107 @default.
- W2033907568 hasRelatedWork W2908786751 @default.
- W2033907568 hasRelatedWork W4288515275 @default.
- W2033907568 hasVolume "41" @default.
- W2033907568 isParatext "false" @default.
- W2033907568 isRetracted "false" @default.
- W2033907568 magId "2033907568" @default.
- W2033907568 workType "article" @default.