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- W2033924871 abstract "The synthesis and biological evaluation of ten Michael acceptors containing potential proteasome inhibitors are described. Cellular targets of azide containing inhibitors Ib and VIIIb were assessed in HEK293T and RAW264.7 cells by a two step labeling strategy, followed by biotin-pulldown, affinity purification, on-bead tryptic digestion and LC-MS2 identification. This strategy appears to be an attractive alternative to gel-based competition assays." @default.
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- W2033924871 date "2010-01-01" @default.
- W2033924871 modified "2023-10-16" @default.
- W2033924871 title "Proteasome selectivity towards Michael acceptor containing oligopeptide-based inhibitors" @default.
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- W2033924871 doi "https://doi.org/10.1039/b924134e" @default.
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