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• W2033945882 abstract "Cytogenesis in the cat retina was studied using tritiated (3H) thymidine autoradiography and nuclear stains. Three zones of cell division were recognized. In the first zone cell cleavage occurs at the outer limiting membrane. The distribution of these mitotic figures is uniform as early as an embryonic age of 29 days (E29) until E50. At about E50 a cold spot, made apparent by the absence of mitotic figures, is evident at the site of the developing area centralis. This spreads to encompass the whole retina by postnatal day 10 (P10). A second zone of cell division was recognized by the presence in the developing inner nuclear layer of 3H-thymidine labelled nuclei which do not migrate to the outer limiting membrane (ventricular surface) to divide. Some of these labelled nuclei are located in regions of the retina where cytogenesis at the ventricular surface has ceased. A third zone was observed in the optic nerve fibre/ganglion cell layers from about E54 until beyond the first postnatal month. This activity gives rise to vascular endothelial cells in the nerve fibre/ganglion cell layers. Once established, the developing vascular cells invade the inner plexiform and inner nuclear layers to form the deeper capillary net." @default.
• W2033945882 created "2016-06-24" @default.
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• W2033945882 date "1985-05-01" @default.
• W2033945882 modified "2023-09-26" @default.
• W2033945882 title "CYTOGENESIS IN THE DEVELOPING RETINA OF THE CAT" @default.
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• W2033945882 doi "https://doi.org/10.1111/j.1442-9071.1985.tb00412.x" @default.
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