FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033966072> ?p ?o ?g. }

• W2033966072 endingPage "916" @default.
• W2033966072 startingPage "908" @default.
• W2033966072 abstract "Background. Obliterative bronchiolitis (OB), mainly mediated by T cells, remains the major cause of morbidity and death in long-term lung transplant. Acute rejection (AR), also a T-cell mediated process, is strongly linked to OB. For unknown reasons, several patients with OB halt their pulmonary function decline and stabilize their obstructive defect for a long period. Our aim was to assess the T-cell activation in blood, induced sputum, and broncho-alveolar lavage during AR, stable OB (sOB), and evolving OB (eOB). Methods. T-cell phenotype and cytokine production were assessed by flow cytometry in these three compartments. Interleukin-4, interferon-γ and transforming growth factor (TGF)-β levels were measured by enzyme-linked immunosorbent assay in blood cell culture supernatants. Results were compared between healthy lung transplant recipients and AR (n=7), sOB (n=7), and eOB (n=13). Results. Stable and evolutive OB were characterized by a Treg, Th1, and Th2 activation, but compared to eOB, Treg and Th2 cells predominated in sOB. A clear Th1 activation was observed in AR. TGF-β was increased in AR and evolving OB. Conclusion. These preliminary results indicate a contrasted T-cell activation profile depending on the clinical conditions. We speculate that Treg cells could counterbalance the Th0 activation seen in evolving OB and participate in stabilization of airway obstruction." @default.
• W2033966072 created "2016-06-24" @default.
• W2033966072 creator A5013061449 @default.
• W2033966072 creator A5031799252 @default.
• W2033966072 creator A5041521620 @default.
• W2033966072 creator A5046414284 @default.
• W2033966072 creator A5052720571 @default.
• W2033966072 creator A5074387792 @default.
• W2033966072 date "2007-10-15" @default.
• W2033966072 modified "2023-10-09" @default.
• W2033966072 title "T Regulatory Cells in Stable Posttransplant Bronchiolitis Obliterans Syndrome" @default.
• W2033966072 cites W1550148707 @default.
• W2033966072 cites W1963928756 @default.
• W2033966072 cites W1966175203 @default.
• W2033966072 cites W1967337145 @default.
• W2033966072 cites W1977027086 @default.
• W2033966072 cites W1982009081 @default.
• W2033966072 cites W1984249600 @default.
• W2033966072 cites W1985973644 @default.
• W2033966072 cites W1986496468 @default.
• W2033966072 cites W1988041880 @default.
• W2033966072 cites W2007726213 @default.
• W2033966072 cites W2014307037 @default.
• W2033966072 cites W2019984014 @default.
• W2033966072 cites W2020269918 @default.
• W2033966072 cites W2021305251 @default.
• W2033966072 cites W2026870867 @default.
• W2033966072 cites W2027669421 @default.
• W2033966072 cites W2035876896 @default.
• W2033966072 cites W2045720698 @default.
• W2033966072 cites W2060901634 @default.
• W2033966072 cites W2061401632 @default.
• W2033966072 cites W2065958451 @default.
• W2033966072 cites W2070960562 @default.
• W2033966072 cites W2073408482 @default.
• W2033966072 cites W2075325535 @default.
• W2033966072 cites W2087040667 @default.
• W2033966072 cites W2095435806 @default.
• W2033966072 cites W2108898696 @default.
• W2033966072 cites W2113019087 @default.
• W2033966072 cites W2117590388 @default.
• W2033966072 cites W2119679341 @default.
• W2033966072 cites W2132227824 @default.
• W2033966072 cites W2145067755 @default.
• W2033966072 cites W2156964052 @default.
• W2033966072 cites W4231860663 @default.
• W2033966072 cites W4235523194 @default.
• W2033966072 doi "https://doi.org/10.1097/01.tp.0000281408.20686.cb" @default.
• W2033966072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17984845" @default.
• W2033966072 hasPublicationYear "2007" @default.
• W2033966072 type Work @default.
• W2033966072 sameAs 2033966072 @default.
• W2033966072 citedByCount "28" @default.
• W2033966072 countsByYear W20339660722012 @default.
• W2033966072 countsByYear W20339660722013 @default.
• W2033966072 countsByYear W20339660722014 @default.
• W2033966072 countsByYear W20339660722015 @default.
• W2033966072 countsByYear W20339660722016 @default.
• W2033966072 countsByYear W20339660722019 @default.
• W2033966072 countsByYear W20339660722020 @default.
• W2033966072 countsByYear W20339660722021 @default.
• W2033966072 countsByYear W20339660722022 @default.
• W2033966072 countsByYear W20339660722023 @default.
• W2033966072 crossrefType "journal-article" @default.
• W2033966072 hasAuthorship W2033966072A5013061449 @default.
• W2033966072 hasAuthorship W2033966072A5031799252 @default.
• W2033966072 hasAuthorship W2033966072A5041521620 @default.
• W2033966072 hasAuthorship W2033966072A5046414284 @default.
• W2033966072 hasAuthorship W2033966072A5052720571 @default.
• W2033966072 hasAuthorship W2033966072A5074387792 @default.
• W2033966072 hasBestOaLocation W20339660721 @default.
• W2033966072 hasConcept C118131993 @default.
• W2033966072 hasConcept C126322002 @default.
• W2033966072 hasConcept C142724271 @default.
• W2033966072 hasConcept C203014093 @default.
• W2033966072 hasConcept C2776090121 @default.
• W2033966072 hasConcept C2776301714 @default.
• W2033966072 hasConcept C2776739411 @default.
• W2033966072 hasConcept C2777714996 @default.
• W2033966072 hasConcept C2778690821 @default.
• W2033966072 hasConcept C2778821649 @default.
• W2033966072 hasConcept C2781069245 @default.
• W2033966072 hasConcept C2781448352 @default.
• W2033966072 hasConcept C534529494 @default.
• W2033966072 hasConcept C553184892 @default.
• W2033966072 hasConcept C71924100 @default.
• W2033966072 hasConcept C8891405 @default.
• W2033966072 hasConceptScore W2033966072C118131993 @default.
• W2033966072 hasConceptScore W2033966072C126322002 @default.
• W2033966072 hasConceptScore W2033966072C142724271 @default.
• W2033966072 hasConceptScore W2033966072C203014093 @default.
• W2033966072 hasConceptScore W2033966072C2776090121 @default.
• W2033966072 hasConceptScore W2033966072C2776301714 @default.
• W2033966072 hasConceptScore W2033966072C2776739411 @default.
• W2033966072 hasConceptScore W2033966072C2777714996 @default.
• W2033966072 hasConceptScore W2033966072C2778690821 @default.
• W2033966072 hasConceptScore W2033966072C2778821649 @default.
• W2033966072 hasConceptScore W2033966072C2781069245 @default.

• next