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- W2033992901 abstract "During the past two years hydralazine hydrochloride (1-hydrazinophthalazine hydrochloride; Apresoline) has been used extensively in the treatment of hypertension. Its reputed ability to reduce arterial pressure through its central action 1 and to increase renal circulation 2 accounts in part for its usefulness as an antihypertensive agent. A syndrome, however, appeared among patients using hydralazine, with symptoms which ranged from mild migratory arthralgic pains to symptoms resembling early acute rheumatoid arthritis or acute systemic lupus erythematosus, according to Dustan and his group * and to Perry and Schroeder.† Other isolated cases reported in the recent literature include those of Manter, 7 Feder, 8 Reinhardt and Waldron, 9 and Shackman and associates. 10 Kaufman 11 reported a case of pancytopenia due to hydralazine. This report is an analysis of the late reactions in a group of patients treated with oral administrations of hydralazine" @default.
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- W2033992901 date "1956-12-01" @default.
- W2033992901 modified "2023-09-23" @default.
- W2033992901 title "Rheumatoid and Lupus-Erythematosus-like Syndromes" @default.
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- W2033992901 doi "https://doi.org/10.1001/archderm.1956.01550120060013" @default.
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