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• W2034002525 startingPage "203" @default.
• W2034002525 abstract "Published studies have reported a wide range of sensitivities and specificities for computed tomographic (CT) colonography for polyp detection, generating controversy regarding its diagnostic accuracy.A meta-analysis of published studies comparing the accuracies of CT colonography and colonoscopy for polyp detection was performed. The pooled per-patient sensitivities and specificities were calculated at various thresholds for polyp size. Summary receiver operating characteristic (sROC) curves were also constructed.Thirty studies were included in the meta-analysis of CT colonography. The pooled per-patient sensitivity of CT colonography was higher for polyps greater than 10 mm (0.82, 95% confidence interval [CI], 0.76-0.88) compared with polyps 6 to 10 mm (0.63, 95% CI, 0.52-0.75) and polyps 0 to 5 mm (0.56, 95% CI, 0.42-0.70). Similarly, the exact area under the sROC curve (area +/- standard error) was higher using a threshold greater than 10 mm (0.898 +/- 0.063) compared with thresholds of greater than 5 mm and any size (0.884 +/- 0.033 and 0.822 +/- 0.059, respectively). There were no significant differences in the diagnostic characteristics of 2-dimensional versus 3-dimensional CT colonography. At a threshold greater than 5 mm, the exact area under the sROC curve was significantly higher for endoscopic colonoscopy compared with CT colonography (0.998 +/- 0.006 vs 0.884 +/- 0.033, P < .005).CT colonography has a reasonable sensitivity and specificity for detecting large polyps but was less accurate than endoscopic colonoscopy for smaller polyps. Thus, CT colonography may not be a reasonable alternative in situations in which a small polyp may be clinically relevant." @default.
• W2034002525 created "2016-06-24" @default.
• W2034002525 creator A5009314732 @default.
• W2034002525 creator A5017763176 @default.
• W2034002525 date "2007-03-01" @default.
• W2034002525 modified "2023-10-18" @default.
• W2034002525 title "Meta-analysis Comparing CT Colonography, Air Contrast Barium Enema, and Colonoscopy" @default.
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• W2034002525 doi "https://doi.org/10.1016/j.amjmed.2006.05.061" @default.
• W2034002525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17349438" @default.
• W2034002525 hasPublicationYear "2007" @default.
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