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• W2034004314 endingPage "171" @default.
• W2034004314 startingPage "162" @default.
• W2034004314 abstract "For a long time, autophagy has been mainly studied in yeast or mammalian cell lines, and assays for analyzing autophagy in these models have been well described. More recently, the involvement of autophagy in various physiological functions has been investigated in multicellular organisms. Modification of autophagy flux is involved in developmental processes, resistance to stress conditions, aging, cell death and multiple pathologies. So, the use of animal models is essential to understand these processes in the context of different cell types and during the whole life. For ten years, the nematode Caenorhabditis elegans has emerged as a powerful model to analyze autophagy in physiological or pathological contexts. In this article, we present some of the established approaches and the emerging tools available to monitor and manipulate autophagy in C. elegans, and discuss their advantages and limitations." @default.
• W2034004314 created "2016-06-24" @default.
• W2034004314 creator A5009973714 @default.
• W2034004314 creator A5057007532 @default.
• W2034004314 creator A5060439686 @default.
• W2034004314 date "2015-03-01" @default.
• W2034004314 modified "2023-10-18" @default.
• W2034004314 title "Tools and methods to analyze autophagy in C. elegans" @default.
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• W2034004314 doi "https://doi.org/10.1016/j.ymeth.2014.11.019" @default.
• W2034004314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25484340" @default.
• W2034004314 hasPublicationYear "2015" @default.
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