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- W2034007586 abstract "Ultrastructural H2O2 producing sites in guinea pig peritoneal (PM) and alveolar (AM) macrophages stimulated with soluble stimuli were studied using a cerium technique. Electron-dense deposits resulting from H2O2 and CeCl3 reactions were observed on the contacted surface of aggregated PM plasma membranes stimulated by formyl-methionyl-leucyl-phenylalanine (FMLP) or phorbol myristate acetate (PMA). The AM stimulated by FMLP or PMA demonstrated no significant cell aggregation or H2O2 production. Although calcium ionophore A23187 did not induce any cell aggregation, deposit formation was apparent on the free surface of plasma membranes. These results indicate that cell-cell contact may have an important role in H2O2 production induced by FMLP and PMA, and that H2O2 production induced by A23187 may not depend on cell aggregation." @default.
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- W2034007586 date "1986-01-01" @default.
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- W2034007586 title "Cytochemistry of plasma membranes activated by phorbol myristate acetate and calcium ionophore in the alveolar and peritoneal macrophages of guinea pigs." @default.
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- W2034007586 doi "https://doi.org/10.1267/ahc.19.465" @default.
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