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- W2034009652 abstract "a renal effect of glycosides, it has not been possible to exclude the influence of changes in hemodynamics and filtered load of electrolytes. Chickens possess a renal-portal circulation. The peritubular concentration of a test substance can be maintained higher on the experimental than on the contralateral control side. Since changes in filtrate composition are equal and bilateral, unilateral changes in urine composition on the experimental side are due to alterations in tubule function. The administration of strophanthidin into one leg of a chicken induces a prompt unilateral increase in Naf excretion and urine pH. If initially elevated, K+ excretion decreases. If initially low, K+ excretion either is unaffected or rises. The increase is less than observed when Na+ excretion is elevated with sodium sulfate. The marked increase in Na+ excretion and associated fall in the excretion of Kf and H+ ions following strophanthidin are presumably due to inhibition of the transport system whereby Naf is reabsorbed in exchange for K+ and H+ ions." @default.
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- W2034009652 date "1958-07-01" @default.
- W2034009652 modified "2023-09-25" @default.
- W2034009652 title "Pancreatic disease: Effects upon the lipids and pancreatic enzymes of the serum" @default.
- W2034009652 doi "https://doi.org/10.1016/0002-9343(58)90261-4" @default.
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