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- W2034013847 abstract "Two general features of metameric patterning in Drosophilaare considered: (1) maintenance of a constant number of metameres (segments or parasegments) in the face of variation in length of the embryo; (2) expression of pattern by on-off switchings of particular genes, with only three or four rows of cells to each element of pattern. For each of these features, the general strategic question is raised: could reaction-diffusion theory account for this? In both cases, it is answered affirmatively. For the second feature, this review contains some hitherto unpublished computer simulations by one of us (K. Y. T.), illustrating that a reaction-diffusion mechanism can be transformed into a patterned switching mechanism by nothing more than compartmenting of the diffusion region. For the scale of three compartments to one pattern repeat unit (representing three rows of cells to a segment) the switching pattern predicted by computation is two-off to one-on. This resembles the pattern of expression of the engrailed gene, posteriorly localized in each segment." @default.
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- W2034013847 date "1988-04-01" @default.
- W2034013847 modified "2023-09-24" @default.
- W2034013847 title "Where may reaction-diffusion mechanisms be operating in metameric patterning ofDrosophila embryos?" @default.
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- W2034013847 doi "https://doi.org/10.1002/bies.950080407" @default.
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