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- W2034015679 abstract "Summary3-Methylcholanthrene, 0.66 mg/g rat, was administered by gastric tube to female Sprague-Dawley rats, age 50 days. This dose was repeated at 10-day intervals 1, 2, 3, or 4 times. Mammary cancer was observed in 77.3% of rats 90 days after a single dose and in 100% of the animals given 2 or more doses of carcinogen. Maximal acceleration of mean tumor induction time was achieved with 3 doses. The number of tumors observed correlated directly with the number of doses administered, a response which appears to be quantitatively additive." @default.
- W2034015679 created "2016-06-24" @default.
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- W2034015679 date "1962-04-01" @default.
- W2034015679 modified "2023-09-25" @default.
- W2034015679 title "Influence of Repeated Doses of 3-Methylcholanthrene at Fixed Intervals on Breast Cancer in Sprague-Dawley Female Rats." @default.
- W2034015679 doi "https://doi.org/10.3181/00379727-109-27331" @default.
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