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- W2034106039 abstract "Two new methods for the synthesis of 2-aminothiazolones from 2-(4-methoxybenzylthio)acetic acids are described. A single reagent and simple experimental conditions are used in the key tandem deprotection−cyclization process. In the first approach 2-aminothiazolones are directly accessed via cyclization of the corresponding N-acylisothioureas. The second complementary approach provides access to a variety of 2-thiomethylthiazolones via cyclization of N-acyldithioimidates. The product 2-thiomethylthiazolones are then efficiently converted to 2-aminothiazolones via amine displacement." @default.
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- W2034106039 date "2008-02-01" @default.
- W2034106039 modified "2023-09-27" @default.
- W2034106039 title "New Methods for the Synthesis of 2-Aminothiazolones" @default.
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- W2034106039 doi "https://doi.org/10.1021/jo702369f" @default.
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