FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034114619> ?p ?o ?g. }

• W2034114619 endingPage "2876" @default.
• W2034114619 startingPage "2868" @default.
• W2034114619 abstract "Vimentin, one of type III intermediate filament (IF) proteins, is expressed not only in mesenchymal cells but also in most types of tumor cells. In the present study, we introduced several types of vimentin mutated at putative phosphorylation sites in its amino-terminal head domain into type III IF-negative T24 cells. Site-specific mutation induced the formation of an unusually long bridge-like IF structure between the unseparated daughter cells, although these mutants formed the filament network similar to wild type in interphase cells. Together with sites phosphorylated by Rho-kinase and protein kinase C (PKC), vimentin-Ser72, which can not be phosphorylated by any known vimentin kinase, was one of the mutation sites essential for this phenotype. We further demonstrated that vimentin-Ser72 was phosphorylated specifically at the cleavage furrow during cytokinesis. These observations suggest the existence of a novel protein kinase responsible for vimentin filament separation through the cleavage furrow-specific vimentin phosphorylation. We propose that Rho-kinase, PKC, and an unidentified vimentin-Ser72 kinase may play important roles in vimentin filament separation during cytokinesis." @default.
• W2034114619 created "2016-06-24" @default.
• W2034114619 creator A5026896048 @default.
• W2034114619 creator A5032552470 @default.
• W2034114619 creator A5033456493 @default.
• W2034114619 creator A5038123003 @default.
• W2034114619 creator A5048500772 @default.
• W2034114619 creator A5053395257 @default.
• W2034114619 creator A5058487072 @default.
• W2034114619 date "2001-05-24" @default.
• W2034114619 modified "2023-10-17" @default.
• W2034114619 title "Protein kinases required for segregation of vimentin filaments in mitotic process" @default.
• W2034114619 cites W1480692165 @default.
• W2034114619 cites W1584847179 @default.
• W2034114619 cites W1613745801 @default.
• W2034114619 cites W1629392288 @default.
• W2034114619 cites W1655914581 @default.
• W2034114619 cites W1969465898 @default.
• W2034114619 cites W1971356903 @default.
• W2034114619 cites W1978265027 @default.
• W2034114619 cites W1990537424 @default.
• W2034114619 cites W1993847783 @default.
• W2034114619 cites W1995011897 @default.
• W2034114619 cites W2007907557 @default.
• W2034114619 cites W2014936697 @default.
• W2034114619 cites W2017101886 @default.
• W2034114619 cites W2025129679 @default.
• W2034114619 cites W2028513320 @default.
• W2034114619 cites W2038537091 @default.
• W2034114619 cites W2046051847 @default.
• W2034114619 cites W2048848497 @default.
• W2034114619 cites W2052090797 @default.
• W2034114619 cites W2052748706 @default.
• W2034114619 cites W2056918775 @default.
• W2034114619 cites W2068514788 @default.
• W2034114619 cites W2082607775 @default.
• W2034114619 cites W2086242462 @default.
• W2034114619 cites W2086524338 @default.
• W2034114619 cites W2088072401 @default.
• W2034114619 cites W2096791952 @default.
• W2034114619 cites W2096960609 @default.
• W2034114619 cites W2111489597 @default.
• W2034114619 cites W2111648618 @default.
• W2034114619 cites W2119161392 @default.
• W2034114619 cites W2119297613 @default.
• W2034114619 cites W2122412289 @default.
• W2034114619 cites W2133263108 @default.
• W2034114619 cites W2134754798 @default.
• W2034114619 cites W2137103231 @default.
• W2034114619 cites W2141287268 @default.
• W2034114619 cites W2142930120 @default.
• W2034114619 cites W2143484805 @default.
• W2034114619 cites W2162529062 @default.
• W2034114619 cites W2169856028 @default.
• W2034114619 cites W2238151361 @default.
• W2034114619 doi "https://doi.org/10.1038/sj.onc.1204407" @default.
• W2034114619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11420699" @default.
• W2034114619 hasPublicationYear "2001" @default.
• W2034114619 type Work @default.
• W2034114619 sameAs 2034114619 @default.
• W2034114619 citedByCount "88" @default.
• W2034114619 countsByYear W20341146192012 @default.
• W2034114619 countsByYear W20341146192013 @default.
• W2034114619 countsByYear W20341146192014 @default.
• W2034114619 countsByYear W20341146192015 @default.
• W2034114619 countsByYear W20341146192016 @default.
• W2034114619 countsByYear W20341146192017 @default.
• W2034114619 countsByYear W20341146192018 @default.
• W2034114619 countsByYear W20341146192019 @default.
• W2034114619 countsByYear W20341146192020 @default.
• W2034114619 countsByYear W20341146192021 @default.
• W2034114619 countsByYear W20341146192022 @default.
• W2034114619 crossrefType "journal-article" @default.
• W2034114619 hasAuthorship W2034114619A5026896048 @default.
• W2034114619 hasAuthorship W2034114619A5032552470 @default.
• W2034114619 hasAuthorship W2034114619A5033456493 @default.
• W2034114619 hasAuthorship W2034114619A5038123003 @default.
• W2034114619 hasAuthorship W2034114619A5048500772 @default.
• W2034114619 hasAuthorship W2034114619A5053395257 @default.
• W2034114619 hasAuthorship W2034114619A5058487072 @default.
• W2034114619 hasBestOaLocation W20341146191 @default.
• W2034114619 hasConcept C11960822 @default.
• W2034114619 hasConcept C134867827 @default.
• W2034114619 hasConcept C142669718 @default.
• W2034114619 hasConcept C147447768 @default.
• W2034114619 hasConcept C1491633281 @default.
• W2034114619 hasConcept C153911025 @default.
• W2034114619 hasConcept C184235292 @default.
• W2034114619 hasConcept C203014093 @default.
• W2034114619 hasConcept C204232928 @default.
• W2034114619 hasConcept C2909370275 @default.
• W2034114619 hasConcept C45472230 @default.
• W2034114619 hasConcept C55493867 @default.
• W2034114619 hasConcept C78383274 @default.
• W2034114619 hasConcept C85813293 @default.
• W2034114619 hasConcept C86803240 @default.
• W2034114619 hasConcept C93304396 @default.
• W2034114619 hasConcept C95444343 @default.

• next