FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034121143> ?p ?o ?g. }

• W2034121143 endingPage "589" @default.
• W2034121143 startingPage "581" @default.
• W2034121143 abstract "Background Cardiovascular diseases are associated with disturbances in calcium metabolism, including increased urinary calcium, vitamin D insufficiency, and decreased bone mineral density. Antihypertensive drugs may increase the risk of falling. However, risk of fracture in patients treated with non-diuretic cardiovascular drugs is largely unknown. Aim We investigated associations between fracture risk and treatment with commonly used cardiovascular drugs: beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, and calcium-channel blockers. Design A population-based pharmaco-epidemiological case–control study with fracture in year 2000 as outcome and drug use during the previous 5 years as exposure. We used nationwide computerized registers to assess individual use of drugs and related these data to individual fracture records and information on socio-economic and health-related confounders. Results We included 124 655 cases that sustained a fracture and 373 962 age and gender-matched controls. After adjustment for potential confounders, risk of any fracture was reduced by 9% [odds ratio (OR) 0.91; 95% confidence interval (CI), 0.88–0.93] in users of beta-blockers, by 6% (OR, 0.94; 95%CI, 0.91–0.96) in users of calcium-channel blockers, and by 7% (OR, 0.93; 95%CI, 0.90–0.96) in users of ACE inhibitors. Moreover, risk of hip fractures was reduced significantly by 7–14% in users of the three groups of drugs. No major differences were found between men and women or in subjects younger or older than 70 years of age. Sub-analyses indicated differences between groups of calcium-channel blockers, as use of non-dihydropyridine drugs was associated with a larger risk reduction than use of dihydropyridine drugs. Conclusion Treatment with beta-blockers, ACE inhibitors, and calcium-channel blockers is associated with a small but significantly reduced risk of fracture." @default.
• W2034121143 created "2016-06-24" @default.
• W2034121143 creator A5064914075 @default.
• W2034121143 creator A5066576087 @default.
• W2034121143 creator A5074502655 @default.
• W2034121143 date "2006-03-01" @default.
• W2034121143 modified "2023-10-16" @default.
• W2034121143 title "Treatment with beta-blockers, ACE inhibitors, and calcium-channel blockers is associated with a reduced fracture risk: a nationwide case–control study" @default.
• W2034121143 cites W1543326103 @default.
• W2034121143 cites W1819440959 @default.
• W2034121143 cites W190574859 @default.
• W2034121143 cites W1942368718 @default.
• W2034121143 cites W1965112376 @default.
• W2034121143 cites W1978348264 @default.
• W2034121143 cites W1978899298 @default.
• W2034121143 cites W1979448723 @default.
• W2034121143 cites W1993924259 @default.
• W2034121143 cites W1994430973 @default.
• W2034121143 cites W1996662605 @default.
• W2034121143 cites W2000445173 @default.
• W2034121143 cites W2005454217 @default.
• W2034121143 cites W2007788429 @default.
• W2034121143 cites W2013094041 @default.
• W2034121143 cites W2021400723 @default.
• W2034121143 cites W2034389648 @default.
• W2034121143 cites W2034478656 @default.
• W2034121143 cites W2039041739 @default.
• W2034121143 cites W2040885091 @default.
• W2034121143 cites W2043957952 @default.
• W2034121143 cites W2046396082 @default.
• W2034121143 cites W2055225139 @default.
• W2034121143 cites W2068461519 @default.
• W2034121143 cites W2076399922 @default.
• W2034121143 cites W2085605596 @default.
• W2034121143 cites W2089301369 @default.
• W2034121143 cites W2089976974 @default.
• W2034121143 cites W2103777411 @default.
• W2034121143 cites W2118864405 @default.
• W2034121143 cites W2122235259 @default.
• W2034121143 cites W2133443655 @default.
• W2034121143 cites W2140452679 @default.
• W2034121143 cites W2147510409 @default.
• W2034121143 cites W2159921044 @default.
• W2034121143 cites W2172270209 @default.
• W2034121143 cites W2201893451 @default.
• W2034121143 cites W45405971 @default.
• W2034121143 doi "https://doi.org/10.1097/01.hjh.0000203845.26690.cb" @default.
• W2034121143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16467662" @default.
• W2034121143 hasPublicationYear "2006" @default.
• W2034121143 type Work @default.
• W2034121143 sameAs 2034121143 @default.
• W2034121143 citedByCount "194" @default.
• W2034121143 countsByYear W20341211432012 @default.
• W2034121143 countsByYear W20341211432013 @default.
• W2034121143 countsByYear W20341211432014 @default.
• W2034121143 countsByYear W20341211432015 @default.
• W2034121143 countsByYear W20341211432016 @default.
• W2034121143 countsByYear W20341211432017 @default.
• W2034121143 countsByYear W20341211432018 @default.
• W2034121143 countsByYear W20341211432019 @default.
• W2034121143 countsByYear W20341211432020 @default.
• W2034121143 countsByYear W20341211432021 @default.
• W2034121143 countsByYear W20341211432022 @default.
• W2034121143 countsByYear W20341211432023 @default.
• W2034121143 crossrefType "journal-article" @default.
• W2034121143 hasAuthorship W2034121143A5064914075 @default.
• W2034121143 hasAuthorship W2034121143A5066576087 @default.
• W2034121143 hasAuthorship W2034121143A5074502655 @default.
• W2034121143 hasConcept C124490489 @default.
• W2034121143 hasConcept C126322002 @default.
• W2034121143 hasConcept C156957248 @default.
• W2034121143 hasConcept C27016395 @default.
• W2034121143 hasConcept C44249647 @default.
• W2034121143 hasConcept C519063684 @default.
• W2034121143 hasConcept C71924100 @default.
• W2034121143 hasConcept C77350462 @default.
• W2034121143 hasConcept C84393581 @default.
• W2034121143 hasConcept C85520022 @default.
• W2034121143 hasConceptScore W2034121143C124490489 @default.
• W2034121143 hasConceptScore W2034121143C126322002 @default.
• W2034121143 hasConceptScore W2034121143C156957248 @default.
• W2034121143 hasConceptScore W2034121143C27016395 @default.
• W2034121143 hasConceptScore W2034121143C44249647 @default.
• W2034121143 hasConceptScore W2034121143C519063684 @default.
• W2034121143 hasConceptScore W2034121143C71924100 @default.
• W2034121143 hasConceptScore W2034121143C77350462 @default.
• W2034121143 hasConceptScore W2034121143C84393581 @default.
• W2034121143 hasConceptScore W2034121143C85520022 @default.
• W2034121143 hasIssue "3" @default.
• W2034121143 hasLocation W20341211431 @default.
• W2034121143 hasLocation W20341211432 @default.
• W2034121143 hasOpenAccess W2034121143 @default.
• W2034121143 hasPrimaryLocation W20341211431 @default.
• W2034121143 hasRelatedWork W1992228662 @default.
• W2034121143 hasRelatedWork W2188664023 @default.
• W2034121143 hasRelatedWork W2481749367 @default.
• W2034121143 hasRelatedWork W2585911331 @default.
• W2034121143 hasRelatedWork W2793477322 @default.

• next