FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034122044> ?p ?o ?g. }

• W2034122044 endingPage "1065" @default.
• W2034122044 startingPage "1059" @default.
• W2034122044 abstract "DNA hybridization plays an important role in medical diagnostics, drug development and biological threat discovery. Despite the wide use of optical hybridization detection, electrochemical methods, and especially covalently attached redox markers, attain an increasing interest. However, one problem is that the number of suppliers of electrochemically labelled oligonucleotides is very limited. This paper reports about the use of the commercially available fluorescence quenching label dabcyl (p-methyl red) as a redox active DNA-marker. We investigated the polarographic, voltammetric and adsorptive stripping voltammetric behaviour of this compound in a TRIS buffer at pH 7.5 and found that two polarographic waves (at −0.48 and −1.28 V vs. Ag/AgCl) can be easily distinguished compared to only one clear signal between −0.4 and −0.7 V in most voltammetric techniques. The alternating-current voltammetric (ACV) signal of a dabcyl-labelled target at a thiollinker-probe-SAM modified gold disk electrode was very clear but small due to a fast and irreversible decay of the reduction product. Despite of this, non-complementary DNA-strands could be discriminated and at 15 min hybridization time, trace amounts down to 50 nM target concentration could be detected. Such electrochemical use of optically active labels could open new possibilities for spectroelectrochemical studies of DNA hybridization." @default.
• W2034122044 created "2016-06-24" @default.
• W2034122044 creator A5044926144 @default.
• W2034122044 creator A5059250180 @default.
• W2034122044 creator A5071554041 @default.
• W2034122044 creator A5082134319 @default.
• W2034122044 date "2005-10-01" @default.
• W2034122044 modified "2023-09-23" @default.
• W2034122044 title "Electrochemical DNA hybridization detection using the fluorescence quenching label dabcyl" @default.
• W2034122044 cites W1545016414 @default.
• W2034122044 cites W1973841955 @default.
• W2034122044 cites W1981606269 @default.
• W2034122044 cites W1986390654 @default.
• W2034122044 cites W1989927836 @default.
• W2034122044 cites W1993434389 @default.
• W2034122044 cites W2009040055 @default.
• W2034122044 cites W2010868612 @default.
• W2034122044 cites W2014021107 @default.
• W2034122044 cites W2019386043 @default.
• W2034122044 cites W2030013968 @default.
• W2034122044 cites W2036315891 @default.
• W2034122044 cites W2039325272 @default.
• W2034122044 cites W2043468628 @default.
• W2034122044 cites W2045636037 @default.
• W2034122044 cites W2050678230 @default.
• W2034122044 cites W2055282988 @default.
• W2034122044 cites W2064784807 @default.
• W2034122044 cites W2067039223 @default.
• W2034122044 cites W2124675518 @default.
• W2034122044 cites W2135718797 @default.
• W2034122044 cites W2140167371 @default.
• W2034122044 cites W2145481047 @default.
• W2034122044 cites W2323088361 @default.
• W2034122044 cites W4236548881 @default.
• W2034122044 doi "https://doi.org/10.1016/j.elecom.2005.08.008" @default.
• W2034122044 hasPublicationYear "2005" @default.
• W2034122044 type Work @default.
• W2034122044 sameAs 2034122044 @default.
• W2034122044 citedByCount "7" @default.
• W2034122044 countsByYear W20341220442013 @default.
• W2034122044 countsByYear W20341220442014 @default.
• W2034122044 crossrefType "journal-article" @default.
• W2034122044 hasAuthorship W2034122044A5044926144 @default.
• W2034122044 hasAuthorship W2034122044A5059250180 @default.
• W2034122044 hasAuthorship W2034122044A5071554041 @default.
• W2034122044 hasAuthorship W2034122044A5082134319 @default.
• W2034122044 hasConcept C113196181 @default.
• W2034122044 hasConcept C121332964 @default.
• W2034122044 hasConcept C121745418 @default.
• W2034122044 hasConcept C129312508 @default.
• W2034122044 hasConcept C130197536 @default.
• W2034122044 hasConcept C147789679 @default.
• W2034122044 hasConcept C160756335 @default.
• W2034122044 hasConcept C17525397 @default.
• W2034122044 hasConcept C179104552 @default.
• W2034122044 hasConcept C185592680 @default.
• W2034122044 hasConcept C188518856 @default.
• W2034122044 hasConcept C21951064 @default.
• W2034122044 hasConcept C43617362 @default.
• W2034122044 hasConcept C52859227 @default.
• W2034122044 hasConcept C552990157 @default.
• W2034122044 hasConcept C55493867 @default.
• W2034122044 hasConcept C55904794 @default.
• W2034122044 hasConcept C62520636 @default.
• W2034122044 hasConcept C91881484 @default.
• W2034122044 hasConceptScore W2034122044C113196181 @default.
• W2034122044 hasConceptScore W2034122044C121332964 @default.
• W2034122044 hasConceptScore W2034122044C121745418 @default.
• W2034122044 hasConceptScore W2034122044C129312508 @default.
• W2034122044 hasConceptScore W2034122044C130197536 @default.
• W2034122044 hasConceptScore W2034122044C147789679 @default.
• W2034122044 hasConceptScore W2034122044C160756335 @default.
• W2034122044 hasConceptScore W2034122044C17525397 @default.
• W2034122044 hasConceptScore W2034122044C179104552 @default.
• W2034122044 hasConceptScore W2034122044C185592680 @default.
• W2034122044 hasConceptScore W2034122044C188518856 @default.
• W2034122044 hasConceptScore W2034122044C21951064 @default.
• W2034122044 hasConceptScore W2034122044C43617362 @default.
• W2034122044 hasConceptScore W2034122044C52859227 @default.
• W2034122044 hasConceptScore W2034122044C552990157 @default.
• W2034122044 hasConceptScore W2034122044C55493867 @default.
• W2034122044 hasConceptScore W2034122044C55904794 @default.
• W2034122044 hasConceptScore W2034122044C62520636 @default.
• W2034122044 hasConceptScore W2034122044C91881484 @default.
• W2034122044 hasIssue "10" @default.
• W2034122044 hasLocation W20341220441 @default.
• W2034122044 hasOpenAccess W2034122044 @default.
• W2034122044 hasPrimaryLocation W20341220441 @default.
• W2034122044 hasRelatedWork W1587111278 @default.
• W2034122044 hasRelatedWork W1972286774 @default.
• W2034122044 hasRelatedWork W2015147731 @default.
• W2034122044 hasRelatedWork W2051690300 @default.
• W2034122044 hasRelatedWork W2052341553 @default.
• W2034122044 hasRelatedWork W2060681933 @default.
• W2034122044 hasRelatedWork W2111050646 @default.
• W2034122044 hasRelatedWork W2151549110 @default.
• W2034122044 hasRelatedWork W2171741770 @default.
• W2034122044 hasRelatedWork W4249945502 @default.

• next