FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034128256> ?p ?o ?g. }

• W2034128256 endingPage "235" @default.
• W2034128256 startingPage "229" @default.
• W2034128256 abstract "The present study investigated the effect of orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the opioid receptor-like 1 (ORL-1) receptor on the expression of cocaine-induced conditioned place preference (CPP) in rats. To extend this study, the new non-peptidic compound Ro 65-6570 (8-acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one), with agonist activity at ORL-1 receptors, was examined. The influence of both compounds on cocaine-induced hyperactivity was also studied. Our experiments indicated that intracerebroventricular (i.c.v.) injection of OFQ/N, at doses of 10 and 20 μ g/rat, significantly suppressed the expression of cocaine-induced place preference. Ro 65-6570 (3 and 6 mg/kg, i.p.) did not change the effect of cocaine, although its acute injection in control rats significantly increased the time spent in the drug-associated compartment of the CPP apparatus. The substances exhibited opposite effects on cocaine-induced hyperactivity (OFQ/N suppressed it but Ro 65-6570 increased it). Our results suggest that the effect of OFQ/N on the expression of cocaine-induced CPP may be a result of its influence on dopamine (DA) neurotransmission in mesolimbic structures. Ro 65-6570 does not share this effect with OFQ/N." @default.
• W2034128256 created "2016-06-24" @default.
• W2034128256 creator A5004897429 @default.
• W2034128256 creator A5004941560 @default.
• W2034128256 creator A5040966351 @default.
• W2034128256 creator A5050197652 @default.
• W2034128256 creator A5091584856 @default.
• W2034128256 date "2002-05-01" @default.
• W2034128256 modified "2023-10-07" @default.
• W2034128256 title "Orphanin FQ/nociceptin but not Ro 65-6570 inhibits the expression of cocaine-induced conditioned place preference" @default.
• W2034128256 cites W1598044684 @default.
• W2034128256 cites W1965663693 @default.
• W2034128256 cites W1980545520 @default.
• W2034128256 cites W1989296681 @default.
• W2034128256 cites W1996561349 @default.
• W2034128256 cites W2003657357 @default.
• W2034128256 cites W2011312876 @default.
• W2034128256 cites W2013380848 @default.
• W2034128256 cites W2016562510 @default.
• W2034128256 cites W2022560389 @default.
• W2034128256 cites W2026689443 @default.
• W2034128256 cites W2027884975 @default.
• W2034128256 cites W2037662305 @default.
• W2034128256 cites W2039237410 @default.
• W2034128256 cites W2040873559 @default.
• W2034128256 cites W2048606952 @default.
• W2034128256 cites W2051455839 @default.
• W2034128256 cites W2058611932 @default.
• W2034128256 cites W2066624199 @default.
• W2034128256 cites W2067645781 @default.
• W2034128256 cites W2092371036 @default.
• W2034128256 cites W2095217951 @default.
• W2034128256 cites W2122592499 @default.
• W2034128256 cites W2124787044 @default.
• W2034128256 cites W2133672910 @default.
• W2034128256 cites W2167810428 @default.
• W2034128256 cites W2169863475 @default.
• W2034128256 cites W2326112613 @default.
• W2034128256 doi "https://doi.org/10.1097/00008877-200205000-00006" @default.
• W2034128256 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12122313" @default.
• W2034128256 hasPublicationYear "2002" @default.
• W2034128256 type Work @default.
• W2034128256 sameAs 2034128256 @default.
• W2034128256 citedByCount "73" @default.
• W2034128256 countsByYear W20341282562012 @default.
• W2034128256 countsByYear W20341282562013 @default.
• W2034128256 countsByYear W20341282562014 @default.
• W2034128256 countsByYear W20341282562016 @default.
• W2034128256 countsByYear W20341282562017 @default.
• W2034128256 countsByYear W20341282562018 @default.
• W2034128256 countsByYear W20341282562019 @default.
• W2034128256 countsByYear W20341282562020 @default.
• W2034128256 countsByYear W20341282562021 @default.
• W2034128256 countsByYear W20341282562022 @default.
• W2034128256 crossrefType "journal-article" @default.
• W2034128256 hasAuthorship W2034128256A5004897429 @default.
• W2034128256 hasAuthorship W2034128256A5004941560 @default.
• W2034128256 hasAuthorship W2034128256A5040966351 @default.
• W2034128256 hasAuthorship W2034128256A5050197652 @default.
• W2034128256 hasAuthorship W2034128256A5091584856 @default.
• W2034128256 hasConcept C120750228 @default.
• W2034128256 hasConcept C125439840 @default.
• W2034128256 hasConcept C126322002 @default.
• W2034128256 hasConcept C134018914 @default.
• W2034128256 hasConcept C159023312 @default.
• W2034128256 hasConcept C160262196 @default.
• W2034128256 hasConcept C170493617 @default.
• W2034128256 hasConcept C185592680 @default.
• W2034128256 hasConcept C2778938600 @default.
• W2034128256 hasConcept C2781063702 @default.
• W2034128256 hasConcept C35124327 @default.
• W2034128256 hasConcept C513476851 @default.
• W2034128256 hasConcept C55493867 @default.
• W2034128256 hasConcept C71924100 @default.
• W2034128256 hasConcept C88016717 @default.
• W2034128256 hasConcept C98274493 @default.
• W2034128256 hasConceptScore W2034128256C120750228 @default.
• W2034128256 hasConceptScore W2034128256C125439840 @default.
• W2034128256 hasConceptScore W2034128256C126322002 @default.
• W2034128256 hasConceptScore W2034128256C134018914 @default.
• W2034128256 hasConceptScore W2034128256C159023312 @default.
• W2034128256 hasConceptScore W2034128256C160262196 @default.
• W2034128256 hasConceptScore W2034128256C170493617 @default.
• W2034128256 hasConceptScore W2034128256C185592680 @default.
• W2034128256 hasConceptScore W2034128256C2778938600 @default.
• W2034128256 hasConceptScore W2034128256C2781063702 @default.
• W2034128256 hasConceptScore W2034128256C35124327 @default.
• W2034128256 hasConceptScore W2034128256C513476851 @default.
• W2034128256 hasConceptScore W2034128256C55493867 @default.
• W2034128256 hasConceptScore W2034128256C71924100 @default.
• W2034128256 hasConceptScore W2034128256C88016717 @default.
• W2034128256 hasConceptScore W2034128256C98274493 @default.
• W2034128256 hasIssue "3" @default.
• W2034128256 hasLocation W20341282561 @default.
• W2034128256 hasLocation W20341282562 @default.
• W2034128256 hasOpenAccess W2034128256 @default.
• W2034128256 hasPrimaryLocation W20341282561 @default.
• W2034128256 hasRelatedWork W1980944689 @default.

• next