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- W2034128304 abstract "ABSTRACT. The immunoassay of human growth hormone utilizing the hemagglutination inhibition reaction has been found to be a reliable method for the measurement of purified human growth hormone and extracts of human anterior pituitary. This method was found to be unreliable when applied to human sera because of nonspecific factors present in most sera which induce hemagglutination inhibition. An extraction procedure has been developed which quantitatively removes growth hormone from the major portion of the serum proteins and eliminates the nonspecific factors. With the use of this serum fraction in the hemagglutination inhibition reaction, growth hormone has been measured in acromegalic patients in the range of 3.5–30 μg/100 ml of serum. The half-life in serum of exogenously administered human growth hormone is approximately 30–50 minutes. Growth hormone levels in normal adults are less than 2 μg/100 ml of serum." @default.
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- W2034128304 modified "2023-09-25" @default.
- W2034128304 title "Immunologic Measurement of Growth Hormone in Human Sera" @default.
- W2034128304 doi "https://doi.org/10.1210/jcem-22-9-865" @default.
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