Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034133045> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2034133045 endingPage "410" @default.
- W2034133045 startingPage "404" @default.
- W2034133045 abstract "The importance of three risk factors--serum total cholesterol, systolic blood pressure, and cigarette smoking--on the risk of new major ischaemic heart disease events in men who already have evidence of ischaemic heart disease was assessed. Data from the initial examination in a large prospective study of cardiovascular disease in middle aged men (the British Regional Heart Study) were used to separate 7710 men into three groups on the basis of a resting electrocardiogram, a standardised chest pain questionnaire, and recall of a doctor9s diagnosis of angina or of a previous heart attack: (group 1) no evidence of ischaemic heart disease (75%), (group 2) evidence of ischaemic heart disease short of a definite myocardial infarction (20%), (group 3) definite myocardial infarction (6%). In the average follow up period of 7.5 years, 443 men suffered a new major event caused by ischaemic heart disease (fatal or non-fatal myocardial infarction or sudden cardiac death). Age standardised event rates were determined for each of the three groups for varying levels of the established risk factors. Cigarette smoking is strongly associated with the event rate in group 1 but in men with existing heart disease, especially group 3, differences in risk between the smoking categories were smaller. The strong relation between systolic blood pressure and event rate persisted in groups 1 and 2 but not in group 3. The positive association between serum concentration of total cholesterol and the event rate was strongest in group 1 and weaker in groups 2 and 3, though it remained highly significant. These observations, taken together with the results of previous prospective studies and intervention trials, suggest that the important association between serum total cholesterol and the risk of heart attack persists in men with pre-existing ischaemic heart disease, including myocardial infarction. Therefore, in these men the reduction of serum total cholesterol concentration may be at least as important as it is in men without evidence of ischaemic heart disease." @default.
- W2034133045 created "2016-06-24" @default.
- W2034133045 creator A5004174170 @default.
- W2034133045 creator A5022391075 @default.
- W2034133045 creator A5023436129 @default.
- W2034133045 creator A5027459975 @default.
- W2034133045 creator A5075489341 @default.
- W2034133045 date "1988-11-01" @default.
- W2034133045 modified "2023-09-27" @default.
- W2034133045 title "The role of risk factors in heart attacks occurring in men with pre-existing ischaemic heart disease." @default.
- W2034133045 cites W103133329 @default.
- W2034133045 cites W1674292665 @default.
- W2034133045 cites W1975134701 @default.
- W2034133045 cites W2033986927 @default.
- W2034133045 cites W2043383629 @default.
- W2034133045 cites W2055680350 @default.
- W2034133045 cites W2060758175 @default.
- W2034133045 cites W2066787081 @default.
- W2034133045 cites W2072134167 @default.
- W2034133045 cites W2072737823 @default.
- W2034133045 cites W2078893656 @default.
- W2034133045 cites W2097437350 @default.
- W2034133045 cites W2123032420 @default.
- W2034133045 cites W2126260878 @default.
- W2034133045 cites W2132117316 @default.
- W2034133045 cites W2137347601 @default.
- W2034133045 cites W2206537004 @default.
- W2034133045 cites W2725187802 @default.
- W2034133045 doi "https://doi.org/10.1136/hrt.60.5.404" @default.
- W2034133045 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1216598" @default.
- W2034133045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3203034" @default.
- W2034133045 hasPublicationYear "1988" @default.
- W2034133045 type Work @default.
- W2034133045 sameAs 2034133045 @default.
- W2034133045 citedByCount "27" @default.
- W2034133045 countsByYear W20341330452012 @default.
- W2034133045 countsByYear W20341330452014 @default.
- W2034133045 crossrefType "journal-article" @default.
- W2034133045 hasAuthorship W2034133045A5004174170 @default.
- W2034133045 hasAuthorship W2034133045A5022391075 @default.
- W2034133045 hasAuthorship W2034133045A5023436129 @default.
- W2034133045 hasAuthorship W2034133045A5027459975 @default.
- W2034133045 hasAuthorship W2034133045A5075489341 @default.
- W2034133045 hasBestOaLocation W20341330451 @default.
- W2034133045 hasConcept C126322002 @default.
- W2034133045 hasConcept C164705383 @default.
- W2034133045 hasConcept C2778425758 @default.
- W2034133045 hasConcept C2778704086 @default.
- W2034133045 hasConcept C2779134260 @default.
- W2034133045 hasConcept C2780074459 @default.
- W2034133045 hasConcept C500558357 @default.
- W2034133045 hasConcept C50440223 @default.
- W2034133045 hasConcept C71924100 @default.
- W2034133045 hasConcept C84393581 @default.
- W2034133045 hasConceptScore W2034133045C126322002 @default.
- W2034133045 hasConceptScore W2034133045C164705383 @default.
- W2034133045 hasConceptScore W2034133045C2778425758 @default.
- W2034133045 hasConceptScore W2034133045C2778704086 @default.
- W2034133045 hasConceptScore W2034133045C2779134260 @default.
- W2034133045 hasConceptScore W2034133045C2780074459 @default.
- W2034133045 hasConceptScore W2034133045C500558357 @default.
- W2034133045 hasConceptScore W2034133045C50440223 @default.
- W2034133045 hasConceptScore W2034133045C71924100 @default.
- W2034133045 hasConceptScore W2034133045C84393581 @default.
- W2034133045 hasIssue "5" @default.
- W2034133045 hasLocation W20341330451 @default.
- W2034133045 hasLocation W20341330452 @default.
- W2034133045 hasLocation W20341330453 @default.
- W2034133045 hasLocation W20341330454 @default.
- W2034133045 hasOpenAccess W2034133045 @default.
- W2034133045 hasPrimaryLocation W20341330451 @default.
- W2034133045 hasRelatedWork W1541687106 @default.
- W2034133045 hasRelatedWork W2008223315 @default.
- W2034133045 hasRelatedWork W2008851126 @default.
- W2034133045 hasRelatedWork W2049397185 @default.
- W2034133045 hasRelatedWork W2071338136 @default.
- W2034133045 hasRelatedWork W2237746437 @default.
- W2034133045 hasRelatedWork W2399063111 @default.
- W2034133045 hasRelatedWork W2415765772 @default.
- W2034133045 hasRelatedWork W2417185335 @default.
- W2034133045 hasRelatedWork W4253712241 @default.
- W2034133045 hasVolume "60" @default.
- W2034133045 isParatext "false" @default.
- W2034133045 isRetracted "false" @default.
- W2034133045 magId "2034133045" @default.
- W2034133045 workType "article" @default.