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- W2034133739 abstract "There have been a number of candidates for chemopreventive agents from synthetic drugs and natural compounds suggested to prevent colorectal cancer. However, they have shown modest efficacy in humans. The reason for this could be partly explained by the use of inappropriate models in vitro and in vivo, and the limitation of chemoprevention trials. In Japan, there are no cancer chemopreventive medicines, and few cancer chemoprevention trials to date. In contrast, an increase in the prevalence of colorectal cancer in Japan has forced us to develop more efficient chemopreventive strategies. It is now a good time to review in detail the current status and future prospects for chemoprevention of colorectal cancer with respect to the future development of chemopreventive medicines, particularly using synthetic drugs and natural compounds in Asian populations. The role and mode of action of available synthetic drugs, mainly aspirin and metformin, are reviewed. In addition, the possible impact of natural compounds with anti-inflammatory/immunosuppressive properties, such as ω3 polyunsaturated fatty acid and lactoferrin, are also reviewed." @default.
- W2034133739 created "2016-06-24" @default.
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- W2034133739 date "2013-04-23" @default.
- W2034133739 modified "2023-10-01" @default.
- W2034133739 title "Prevention and Intervention Trials for Colorectal Cancer" @default.
- W2034133739 cites W1269068064 @default.
- W2034133739 cites W1554678066 @default.
- W2034133739 cites W1558367558 @default.
- W2034133739 cites W162792278 @default.
- W2034133739 cites W1895462365 @default.
- W2034133739 cites W1963482427 @default.
- W2034133739 cites W1970658657 @default.
- W2034133739 cites W1971246001 @default.
- W2034133739 cites W1975076018 @default.
- W2034133739 cites W1989742048 @default.
- W2034133739 cites W1993852503 @default.
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- W2034133739 cites W1995591075 @default.
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- W2034133739 cites W2011077759 @default.
- W2034133739 cites W2011089912 @default.
- W2034133739 cites W2013725424 @default.
- W2034133739 cites W2020531708 @default.
- W2034133739 cites W2026791416 @default.
- W2034133739 cites W2026967508 @default.
- W2034133739 cites W2028805137 @default.
- W2034133739 cites W2032794217 @default.
- W2034133739 cites W2036280036 @default.
- W2034133739 cites W2040608814 @default.
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- W2034133739 cites W2059526179 @default.
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- W2034133739 cites W2065861460 @default.
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- W2034133739 cites W2076647438 @default.
- W2034133739 cites W2077991158 @default.
- W2034133739 cites W2079556277 @default.
- W2034133739 cites W2087224686 @default.
- W2034133739 cites W2087949451 @default.
- W2034133739 cites W2088682995 @default.
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- W2034133739 cites W2095762159 @default.
- W2034133739 cites W2097903769 @default.
- W2034133739 cites W2100358697 @default.
- W2034133739 cites W2102937816 @default.
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- W2034133739 cites W2109453679 @default.
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- W2034133739 cites W2120417804 @default.
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- W2034133739 cites W2124690429 @default.
- W2034133739 cites W2127444629 @default.
- W2034133739 cites W2132698289 @default.
- W2034133739 cites W2132852370 @default.
- W2034133739 cites W2137520566 @default.
- W2034133739 cites W2141262449 @default.
- W2034133739 cites W2141806110 @default.
- W2034133739 cites W2143021051 @default.
- W2034133739 cites W2145855590 @default.
- W2034133739 cites W2146654374 @default.
- W2034133739 cites W2148906549 @default.
- W2034133739 cites W2150446149 @default.
- W2034133739 cites W2153611464 @default.
- W2034133739 cites W2154894590 @default.
- W2034133739 cites W2157304020 @default.
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- W2034133739 cites W2166393423 @default.
- W2034133739 cites W2170189325 @default.
- W2034133739 cites W2171460643 @default.
- W2034133739 cites W2336169581 @default.
- W2034133739 cites W2336215030 @default.
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- W2034133739 doi "https://doi.org/10.1093/jjco/hyt053" @default.
- W2034133739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23613189" @default.
- W2034133739 hasPublicationYear "2013" @default.
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