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• W2034137073 abstract "The scope and limitations of the solid-supported synthesis of a bicyclic diketopiperazine, an internal, putative peptide beta-turn mimetic, are presented. The 4CC multicomponent Ugi reaction of alpha-N-Boc-diaminopropionic acid resin ester (an amine input), optically active alpha-bromoacid, aldehyde, and isocyanide is the key step in the proposed synthetic protocol. Application of cyclitive cleavage as the final step led to desired products in high purity." @default.
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• W2034137073 date "2002-09-13" @default.
• W2034137073 modified "2023-10-17" @default.
• W2034137073 title "Solid-Supported Synthesis of Putative Peptide β-Turn Mimetics via Ugi Reaction for Diketopiperazine Formation" @default.
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• W2034137073 doi "https://doi.org/10.1021/cc020029u" @default.
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