FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034137732> ?p ?o ?g. }

• W2034137732 endingPage "280" @default.
• W2034137732 startingPage "272" @default.
• W2034137732 abstract "• Rats fed a high fat diet elicit anxiolytic-like behavior in an elevated plus maze. • High fat diet (HFD) increases plasma corticosterone levels. • Levels are elevated at baseline and following exposure to the elevated plus maze. • Glucocorticoid receptor (GR) immunoreactivity is altered by HFD. • HFD increases GR immunoreactivity in parietal cortex and hypothalamus. • The effects of HFD on behavior do not correlate with corticosterone or GR changes. Previous studies have shown that diet-induced obesity is associated with insulin resistance and impaired feedback control of the hypothalamic-pituitary-adrenal (HPA) axis. The objective of this study was to test the hypothesis that hyper-secretion of glucocorticoid, evoked by feeding rats a high fat (HF) diet for 12 weeks, also influences behavioural and neural responses to the elevated plus-maze (EPM) test of anxiety. HF-fed animals exhibited anxiolytic-like behaviour in the EPM but were also hyperactive in this test. Covariant analysis established that the anxiolytic-like behaviour was not secondary to the increase in activity. The HF diet significantly increased basal levels of plasma corticosterone. The groups exposed to the EPM also displayed increased plasma corticosterone levels compared to the relevant control group, although the increment was smaller in the HF-fed animals. Glucocorticoid receptor (GR) immunoreactivity in the cytoplasmic fraction of parietal cortex and hypothalamus and the particulate fraction of the parietal cortex were increased by HF feeding. The behavioural changes evoked by HF feeding did not correlate significantly with changes in GR immunoreactivity in each treatment group or 5-HT turnover in the brain areas studied. It is concluded that anxiolytic properties evoked in the EPM by high fat feeding are unlikely to be related to the changes in HPA function seen in animals fed this diet." @default.
• W2034137732 created "2016-06-24" @default.
• W2034137732 creator A5010038909 @default.
• W2034137732 creator A5014159327 @default.
• W2034137732 creator A5016819318 @default.
• W2034137732 creator A5056855417 @default.
• W2034137732 date "2015-02-01" @default.
• W2034137732 modified "2023-09-25" @default.
• W2034137732 title "High fat feeding is associated with stimulation of the hypothalamic-pituitary-adrenal axis and reduced anxiety in the rat" @default.
• W2034137732 cites W1969412681 @default.
• W2034137732 cites W1970343398 @default.
• W2034137732 cites W1971200894 @default.
• W2034137732 cites W1978672583 @default.
• W2034137732 cites W1980374662 @default.
• W2034137732 cites W1983644247 @default.
• W2034137732 cites W1992115299 @default.
• W2034137732 cites W1994801797 @default.
• W2034137732 cites W2003716127 @default.
• W2034137732 cites W2005556159 @default.
• W2034137732 cites W2007636259 @default.
• W2034137732 cites W2010564515 @default.
• W2034137732 cites W2016336988 @default.
• W2034137732 cites W2016619393 @default.
• W2034137732 cites W2017638095 @default.
• W2034137732 cites W2039598971 @default.
• W2034137732 cites W2041431737 @default.
• W2034137732 cites W2053140710 @default.
• W2034137732 cites W2060491921 @default.
• W2034137732 cites W2061155921 @default.
• W2034137732 cites W2063842325 @default.
• W2034137732 cites W2066209714 @default.
• W2034137732 cites W2068308990 @default.
• W2034137732 cites W2069303582 @default.
• W2034137732 cites W2070771391 @default.
• W2034137732 cites W2080455415 @default.
• W2034137732 cites W2091396163 @default.
• W2034137732 cites W2093500882 @default.
• W2034137732 cites W2108025834 @default.
• W2034137732 cites W2130784808 @default.
• W2034137732 cites W2139220014 @default.
• W2034137732 cites W2153393568 @default.
• W2034137732 cites W2153727556 @default.
• W2034137732 cites W2167646035 @default.
• W2034137732 cites W2171186447 @default.
• W2034137732 cites W4293247451 @default.
• W2034137732 cites W4294443837 @default.
• W2034137732 doi "https://doi.org/10.1016/j.psyneuen.2014.12.002" @default.
• W2034137732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25544739" @default.
• W2034137732 hasPublicationYear "2015" @default.
• W2034137732 type Work @default.
• W2034137732 sameAs 2034137732 @default.
• W2034137732 citedByCount "42" @default.
• W2034137732 countsByYear W20341377322015 @default.
• W2034137732 countsByYear W20341377322016 @default.
• W2034137732 countsByYear W20341377322017 @default.
• W2034137732 countsByYear W20341377322018 @default.
• W2034137732 countsByYear W20341377322019 @default.
• W2034137732 countsByYear W20341377322020 @default.
• W2034137732 countsByYear W20341377322021 @default.
• W2034137732 countsByYear W20341377322022 @default.
• W2034137732 countsByYear W20341377322023 @default.
• W2034137732 crossrefType "journal-article" @default.
• W2034137732 hasAuthorship W2034137732A5010038909 @default.
• W2034137732 hasAuthorship W2034137732A5014159327 @default.
• W2034137732 hasAuthorship W2034137732A5016819318 @default.
• W2034137732 hasAuthorship W2034137732A5056855417 @default.
• W2034137732 hasConcept C118552586 @default.
• W2034137732 hasConcept C126322002 @default.
• W2034137732 hasConcept C134018914 @default.
• W2034137732 hasConcept C15744967 @default.
• W2034137732 hasConcept C170493617 @default.
• W2034137732 hasConcept C173586616 @default.
• W2034137732 hasConcept C185592680 @default.
• W2034137732 hasConcept C2777003273 @default.
• W2034137732 hasConcept C2777765862 @default.
• W2034137732 hasConcept C2780352252 @default.
• W2034137732 hasConcept C2780841215 @default.
• W2034137732 hasConcept C558461103 @default.
• W2034137732 hasConcept C59493245 @default.
• W2034137732 hasConcept C71315377 @default.
• W2034137732 hasConcept C71924100 @default.
• W2034137732 hasConceptScore W2034137732C118552586 @default.
• W2034137732 hasConceptScore W2034137732C126322002 @default.
• W2034137732 hasConceptScore W2034137732C134018914 @default.
• W2034137732 hasConceptScore W2034137732C15744967 @default.
• W2034137732 hasConceptScore W2034137732C170493617 @default.
• W2034137732 hasConceptScore W2034137732C173586616 @default.
• W2034137732 hasConceptScore W2034137732C185592680 @default.
• W2034137732 hasConceptScore W2034137732C2777003273 @default.
• W2034137732 hasConceptScore W2034137732C2777765862 @default.
• W2034137732 hasConceptScore W2034137732C2780352252 @default.
• W2034137732 hasConceptScore W2034137732C2780841215 @default.
• W2034137732 hasConceptScore W2034137732C558461103 @default.
• W2034137732 hasConceptScore W2034137732C59493245 @default.
• W2034137732 hasConceptScore W2034137732C71315377 @default.
• W2034137732 hasConceptScore W2034137732C71924100 @default.
• W2034137732 hasLocation W20341377321 @default.
• W2034137732 hasLocation W20341377322 @default.

• next