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• W2034138623 abstract "Abstract The burden of painful diabetic peripheral neuropathy (DPN) is a common complication of diabetes. This study expanded on the human burden of painful DPN by quantifying functional and health status impairments among international patients from a randomized, double‐blind, placebo‐controlled trial of painful DPN. Evaluated outcomes measures included: Brief Pain Inventory‐Short Form (mBPI‐sf), EuroQOL 5D, Hospital Anxiety and Depression Scale, and Medical Outcomes Study Sleep Scale. Outcomes were stratified by pain severity using cut‐points: 0 to 10 numeric rating scale (NRS) for average pain (0 to 3: none/mild, 4 to 6: moderate, 7 to 10: severe). Study sample is: 401 patients (163 in Asia, 110 in Latin America and 128 in the Middle East), mostly female (61%) (± standard deviation, SD), age of 57 ± 10 years. Participants reported at least moderate levels of pain severity (mean [± SD] scores on a 0 to 10 NRS for average pain of 5.9 ± 1.8 for Asia, 6.7 ± 1.6 for Latin America, and 6.6 ± 1.7 for the Middle East). Mean (± SD) values on the mBPI‐sf Pain Interference Index were 4.7 ± 2.3 for Asia, 5.6 ± 2.1 for Latin America, and 5.5 ± 2.3 for the Middle East. Patients in all 3 regions reported difficulties with functioning, sleep, and overall health status, which increased with higher pain severity levels. Patients in Asia had substantial impairments; however, they reported less serious problems than the other regions. These data are consistent with painful DPN being a burdensome condition worldwide: people with poorly managed neuropathic pain report a substantial burden of disease." @default.
• W2034138623 created "2016-06-24" @default.
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• W2034138623 date "2009-01-01" @default.
• W2034138623 modified "2023-10-15" @default.
• W2034138623 title "Cross-National Burden of Painful Diabetic Peripheral Neuropathy in Asia, Latin America, and the Middle East" @default.
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• W2034138623 doi "https://doi.org/10.1111/j.1533-2500.2008.00249.x" @default.
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