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• W2034141381 abstract "Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production. The routes in Complex I for superoxide formation and for adrenochrome reduction appear to be different, since they have a different sensitivity to Complex I inhibitors. The results are discussed in terms of current assays for superoxide detection and of pathologies linked to catecholamine oxidation." @default.
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• W2034141381 date "2006-03-01" @default.
• W2034141381 modified "2023-09-24" @default.
• W2034141381 title "Redox cycling of adrenaline and adrenochrome catalysed by mitochondrial Complex I" @default.
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• W2034141381 doi "https://doi.org/10.1016/j.abb.2006.01.010" @default.
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