Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034143786> ?p ?o ?g. }
- W2034143786 abstract "Previously, our group reported that sulforaphane (SFN), a naturally occurring chemopreventive agent from cruciferous vegetables, effectively inhibits the proliferation of KB and YD-10B human oral squamous carcinoma cells by causing apoptosis. In this study, treatment of 20 and 40 microM of SFN for 12 h caused a cell cycle arrest in the G(2)/M phase. Cell cycle arrest induced by SFN was associated with a significant increase in the p21 protein level and a decrease in cyclin B expression, but there was no change in the cyclin A protein level. In addition, SFN increased the p21 promoter activity significantly. Furthermore, SFN induced p21 protein expression in a nude mouse xenograft model suggesting that SFN is a potent inducer of the p21 protein in human oral squamous carcinoma cells. These findings show that SFN is a promising candidate for molecular-targeting chemotherapy against human oral squamous cell carcinoma." @default.
- W2034143786 created "2016-06-24" @default.
- W2034143786 creator A5009660402 @default.
- W2034143786 creator A5009736817 @default.
- W2034143786 creator A5011547643 @default.
- W2034143786 creator A5012789845 @default.
- W2034143786 creator A5016234851 @default.
- W2034143786 creator A5018846918 @default.
- W2034143786 creator A5023724281 @default.
- W2034143786 creator A5027026269 @default.
- W2034143786 creator A5028241736 @default.
- W2034143786 creator A5032565249 @default.
- W2034143786 creator A5065680403 @default.
- W2034143786 creator A5076661925 @default.
- W2034143786 creator A5085428796 @default.
- W2034143786 date "2009-01-01" @default.
- W2034143786 modified "2023-09-28" @default.
- W2034143786 title "Sulforaphane Increases Cyclin-Dependent Kinase Inhibitor, p21 Protein in Human Oral Carcinoma Cells and Nude Mouse Animal Model to Induce G2/M Cell Cycle Arrest" @default.
- W2034143786 cites W1509669696 @default.
- W2034143786 cites W1638902273 @default.
- W2034143786 cites W1645404114 @default.
- W2034143786 cites W1859231335 @default.
- W2034143786 cites W1886614022 @default.
- W2034143786 cites W1966954300 @default.
- W2034143786 cites W1977341075 @default.
- W2034143786 cites W1985264467 @default.
- W2034143786 cites W1996413533 @default.
- W2034143786 cites W1999395072 @default.
- W2034143786 cites W2005382866 @default.
- W2034143786 cites W2006256205 @default.
- W2034143786 cites W2009616940 @default.
- W2034143786 cites W2011994306 @default.
- W2034143786 cites W2015519364 @default.
- W2034143786 cites W2016823780 @default.
- W2034143786 cites W2021312876 @default.
- W2034143786 cites W2028416991 @default.
- W2034143786 cites W2028501450 @default.
- W2034143786 cites W2029459160 @default.
- W2034143786 cites W2035568149 @default.
- W2034143786 cites W2065942363 @default.
- W2034143786 cites W2070061120 @default.
- W2034143786 cites W2071113489 @default.
- W2034143786 cites W2072088194 @default.
- W2034143786 cites W2082785987 @default.
- W2034143786 cites W2087546871 @default.
- W2034143786 cites W2089218510 @default.
- W2034143786 cites W2093837468 @default.
- W2034143786 cites W2094105923 @default.
- W2034143786 cites W2118287650 @default.
- W2034143786 cites W2119728044 @default.
- W2034143786 cites W2128980548 @default.
- W2034143786 cites W2136700586 @default.
- W2034143786 cites W2142026128 @default.
- W2034143786 cites W2145028201 @default.
- W2034143786 cites W2149089218 @default.
- W2034143786 cites W2158430000 @default.
- W2034143786 cites W2163895012 @default.
- W2034143786 cites W2168737016 @default.
- W2034143786 cites W2171051548 @default.
- W2034143786 cites W226375715 @default.
- W2034143786 cites W48596264 @default.
- W2034143786 doi "https://doi.org/10.3164/jcbn.09-65" @default.
- W2034143786 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2803134" @default.
- W2034143786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20104266" @default.
- W2034143786 hasPublicationYear "2009" @default.
- W2034143786 type Work @default.
- W2034143786 sameAs 2034143786 @default.
- W2034143786 citedByCount "5" @default.
- W2034143786 countsByYear W20341437862018 @default.
- W2034143786 countsByYear W20341437862019 @default.
- W2034143786 countsByYear W20341437862022 @default.
- W2034143786 crossrefType "journal-article" @default.
- W2034143786 hasAuthorship W2034143786A5009660402 @default.
- W2034143786 hasAuthorship W2034143786A5009736817 @default.
- W2034143786 hasAuthorship W2034143786A5011547643 @default.
- W2034143786 hasAuthorship W2034143786A5012789845 @default.
- W2034143786 hasAuthorship W2034143786A5016234851 @default.
- W2034143786 hasAuthorship W2034143786A5018846918 @default.
- W2034143786 hasAuthorship W2034143786A5023724281 @default.
- W2034143786 hasAuthorship W2034143786A5027026269 @default.
- W2034143786 hasAuthorship W2034143786A5028241736 @default.
- W2034143786 hasAuthorship W2034143786A5032565249 @default.
- W2034143786 hasAuthorship W2034143786A5065680403 @default.
- W2034143786 hasAuthorship W2034143786A5076661925 @default.
- W2034143786 hasAuthorship W2034143786A5085428796 @default.
- W2034143786 hasBestOaLocation W20341437861 @default.
- W2034143786 hasConcept C105696609 @default.
- W2034143786 hasConcept C120089663 @default.
- W2034143786 hasConcept C120504264 @default.
- W2034143786 hasConcept C124320809 @default.
- W2034143786 hasConcept C185592680 @default.
- W2034143786 hasConcept C190283241 @default.
- W2034143786 hasConcept C2778437423 @default.
- W2034143786 hasConcept C2780278673 @default.
- W2034143786 hasConcept C2780841255 @default.
- W2034143786 hasConcept C29537977 @default.
- W2034143786 hasConcept C502942594 @default.
- W2034143786 hasConcept C55493867 @default.
- W2034143786 hasConcept C62112901 @default.
- W2034143786 hasConcept C86803240 @default.