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- W2034143798 abstract "A mutant EcoRI endonuclease restriction site has been identified in 3 of 37 Black subjects and in 2 sibs of one of these persons. This mutation was not encountered in 13 Whites. It is located approximately 6 kilobases inside the normal site in the 5' flanking sequence of the alpha-globin chain complex. The shortened alpha-globin gene-bearing segment produced in the EcoRI digest produces a restriction map similar to that observed for the common alpha-globin gene deletion observed in the Black population. However, the restriction map with BamHI is normal, confirming that all four alpha loci are present." @default.
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- W2034143798 date "1981-11-01" @default.
- W2034143798 modified "2023-09-23" @default.
- W2034143798 title "A common mutant EcoRI restriction endonuclease site in the 5' flanking portion of the human alpha-globin gene." @default.
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- W2034143798 doi "https://doi.org/10.1073/pnas.78.11.7056" @default.
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