FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034144554> ?p ?o ?g. }

• W2034144554 endingPage "19" @default.
• W2034144554 startingPage "15" @default.
• W2034144554 abstract "Matrine (Mat), a component extracted from Sophora flavescens Ait, has a wide spectrum of pharmacological effects. Glycyrrhizin (Gly), a major active constituent of licorice (Glycyrrhiza glabra) root, has various pharmacological effects. Gly and Mat are ancillary drugs used clinically in China for protection of liver function and treatment of tumors. However, habitual administration of Gly may cause adverse effects marked by the development of pseudohypercorticosteroidism. This work was designed to see whether combination use of Gly and Mat could offer better liver protective and anti-hepatocarcinogenic effects than Gly or Mat alone, and whether it could reduce the adverse effects of Gly alone by acetaminophen-induced hepatotoxicity, diethylnitrosamine-induced hepatocarcinogenesis, induction of immunosuppression, albumen-induced swelling of rat hind paws. The results showed that compared with Gly or Mat alone, Gly + Mat reduced the mortality of acetaminophen overdosed mice more effectively, attenuate acetaminophen-induced hepatotoxicity, and reduced the number and area of γ-GT positive foci, thus protecting liver function and preventing HCC from occurring. In addition, Gly + Mat had a protective effect on immunosuppression, a strong non-specific anti-inflammatory effect, and an effect of reducing the incidence of sodium and water retention." @default.
• W2034144554 created "2016-06-24" @default.
• W2034144554 creator A5024380956 @default.
• W2034144554 creator A5032396875 @default.
• W2034144554 creator A5040907912 @default.
• W2034144554 creator A5089489848 @default.
• W2034144554 date "2009-09-01" @default.
• W2034144554 modified "2023-10-11" @default.
• W2034144554 title "Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine" @default.
• W2034144554 cites W1977287866 @default.
• W2034144554 cites W1982491218 @default.
• W2034144554 cites W1982584241 @default.
• W2034144554 cites W1988396798 @default.
• W2034144554 cites W1992314595 @default.
• W2034144554 cites W1994561845 @default.
• W2034144554 cites W2003873847 @default.
• W2034144554 cites W2015098698 @default.
• W2034144554 cites W2017628854 @default.
• W2034144554 cites W2046174392 @default.
• W2034144554 cites W2062976963 @default.
• W2034144554 cites W2064333649 @default.
• W2034144554 cites W2068596545 @default.
• W2034144554 cites W2081041695 @default.
• W2034144554 cites W2084931261 @default.
• W2034144554 cites W2096868960 @default.
• W2034144554 cites W2103719674 @default.
• W2034144554 cites W2113432742 @default.
• W2034144554 cites W2135093951 @default.
• W2034144554 cites W2150171095 @default.
• W2034144554 cites W2156460192 @default.
• W2034144554 doi "https://doi.org/10.1016/j.cbi.2009.04.013" @default.
• W2034144554 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19426721" @default.
• W2034144554 hasPublicationYear "2009" @default.
• W2034144554 type Work @default.
• W2034144554 sameAs 2034144554 @default.
• W2034144554 citedByCount "91" @default.
• W2034144554 countsByYear W20341445542012 @default.
• W2034144554 countsByYear W20341445542013 @default.
• W2034144554 countsByYear W20341445542014 @default.
• W2034144554 countsByYear W20341445542015 @default.
• W2034144554 countsByYear W20341445542016 @default.
• W2034144554 countsByYear W20341445542017 @default.
• W2034144554 countsByYear W20341445542018 @default.
• W2034144554 countsByYear W20341445542019 @default.
• W2034144554 countsByYear W20341445542020 @default.
• W2034144554 countsByYear W20341445542021 @default.
• W2034144554 countsByYear W20341445542022 @default.
• W2034144554 countsByYear W20341445542023 @default.
• W2034144554 crossrefType "journal-article" @default.
• W2034144554 hasAuthorship W2034144554A5024380956 @default.
• W2034144554 hasAuthorship W2034144554A5032396875 @default.
• W2034144554 hasAuthorship W2034144554A5040907912 @default.
• W2034144554 hasAuthorship W2034144554A5089489848 @default.
• W2034144554 hasConcept C118552586 @default.
• W2034144554 hasConcept C142724271 @default.
• W2034144554 hasConcept C185592680 @default.
• W2034144554 hasConcept C188947578 @default.
• W2034144554 hasConcept C197934379 @default.
• W2034144554 hasConcept C204787440 @default.
• W2034144554 hasConcept C2776332754 @default.
• W2034144554 hasConcept C2776545273 @default.
• W2034144554 hasConcept C2776625710 @default.
• W2034144554 hasConcept C2776637226 @default.
• W2034144554 hasConcept C2778722691 @default.
• W2034144554 hasConcept C2778993495 @default.
• W2034144554 hasConcept C2779655422 @default.
• W2034144554 hasConcept C2779703632 @default.
• W2034144554 hasConcept C71924100 @default.
• W2034144554 hasConcept C98274493 @default.
• W2034144554 hasConceptScore W2034144554C118552586 @default.
• W2034144554 hasConceptScore W2034144554C142724271 @default.
• W2034144554 hasConceptScore W2034144554C185592680 @default.
• W2034144554 hasConceptScore W2034144554C188947578 @default.
• W2034144554 hasConceptScore W2034144554C197934379 @default.
• W2034144554 hasConceptScore W2034144554C204787440 @default.
• W2034144554 hasConceptScore W2034144554C2776332754 @default.
• W2034144554 hasConceptScore W2034144554C2776545273 @default.
• W2034144554 hasConceptScore W2034144554C2776625710 @default.
• W2034144554 hasConceptScore W2034144554C2776637226 @default.
• W2034144554 hasConceptScore W2034144554C2778722691 @default.
• W2034144554 hasConceptScore W2034144554C2778993495 @default.
• W2034144554 hasConceptScore W2034144554C2779655422 @default.
• W2034144554 hasConceptScore W2034144554C2779703632 @default.
• W2034144554 hasConceptScore W2034144554C71924100 @default.
• W2034144554 hasConceptScore W2034144554C98274493 @default.
• W2034144554 hasIssue "1" @default.
• W2034144554 hasLocation W20341445541 @default.
• W2034144554 hasLocation W20341445542 @default.
• W2034144554 hasOpenAccess W2034144554 @default.
• W2034144554 hasPrimaryLocation W20341445541 @default.
• W2034144554 hasRelatedWork W2017379001 @default.
• W2034144554 hasRelatedWork W2067853962 @default.
• W2034144554 hasRelatedWork W2176054211 @default.
• W2034144554 hasRelatedWork W2281723475 @default.
• W2034144554 hasRelatedWork W2317601229 @default.
• W2034144554 hasRelatedWork W2322755911 @default.
• W2034144554 hasRelatedWork W2348229829 @default.
• W2034144554 hasRelatedWork W2388507888 @default.

• next