Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034146801> ?p ?o ?g. }
- W2034146801 endingPage "76" @default.
- W2034146801 startingPage "70" @default.
- W2034146801 abstract "We report here the establishment of a new cell line, Karpas 620 (K620), from the peripheral blood of an elderly woman with an IgG-kappa plasma cell leukaemia (PCL). The line has the same hypotetraploid karyotype as the fresh cells from the patient. The cultured cells have the ultrastructural appearance of plasma cells with abundant rough endoplasmic reticulum (RER) and secrete kappa light chain. They are positive for surface antigens HLA DR, and WR17 (CD 37) and negative for CD1, CD3, CD4 and CD8. Using high resolution (HR) cytogenetic analysis it has been possible to identify all the marker chromosomes including several rearrangements commonly seen in malignancies of B cell lineage. These are a 14q + marker with a typical ‘Burkitt’morphology der(14)(pter→q32.3::8q24.1→qter) but with no reciprocal 8q–, and three translocations involving chromosome 11 at q 13 with partners other than chromosome 14, namely 1q32.1, 8q24.22 and 13q14.3. An earlier report of molecular studies on the DNA of K620 has shown a rearrangement near the region on 11q13 designated BCL-1 (Rabbitts et al, 1988). This is the first report of a rearrangement in the region of 11q 13 in a cell line originating from a case of plasma cell leukaemia." @default.
- W2034146801 created "2016-06-24" @default.
- W2034146801 creator A5001432477 @default.
- W2034146801 creator A5019802706 @default.
- W2034146801 creator A5026348330 @default.
- W2034146801 creator A5028443519 @default.
- W2034146801 creator A5028883400 @default.
- W2034146801 creator A5042951664 @default.
- W2034146801 creator A5080213567 @default.
- W2034146801 creator A5084568832 @default.
- W2034146801 creator A5080630464 @default.
- W2034146801 date "1990-01-01" @default.
- W2034146801 modified "2023-10-16" @default.
- W2034146801 title "A new human plasma cell line, Karpas 620, with translocations involving chromosomes 1, 11 and 14" @default.
- W2034146801 cites W1489850871 @default.
- W2034146801 cites W1585188078 @default.
- W2034146801 cites W1589708294 @default.
- W2034146801 cites W1968900701 @default.
- W2034146801 cites W1969783034 @default.
- W2034146801 cites W1970748912 @default.
- W2034146801 cites W1979652116 @default.
- W2034146801 cites W1981062512 @default.
- W2034146801 cites W1985384063 @default.
- W2034146801 cites W1993585891 @default.
- W2034146801 cites W2006321868 @default.
- W2034146801 cites W2009039088 @default.
- W2034146801 cites W2011163773 @default.
- W2034146801 cites W2022809685 @default.
- W2034146801 cites W2025646176 @default.
- W2034146801 cites W2030789354 @default.
- W2034146801 cites W2035642640 @default.
- W2034146801 cites W2039276750 @default.
- W2034146801 cites W2041780798 @default.
- W2034146801 cites W2048179528 @default.
- W2034146801 cites W2059873168 @default.
- W2034146801 cites W2062530202 @default.
- W2034146801 cites W2087312457 @default.
- W2034146801 cites W2087653506 @default.
- W2034146801 cites W2093375792 @default.
- W2034146801 cites W2140587752 @default.
- W2034146801 cites W2146696458 @default.
- W2034146801 cites W2279214483 @default.
- W2034146801 cites W2370949147 @default.
- W2034146801 cites W2431948991 @default.
- W2034146801 cites W344306772 @default.
- W2034146801 cites W85233391 @default.
- W2034146801 doi "https://doi.org/10.1111/j.1365-2141.1990.tb02540.x" @default.
- W2034146801 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2310698" @default.
- W2034146801 hasPublicationYear "1990" @default.
- W2034146801 type Work @default.
- W2034146801 sameAs 2034146801 @default.
- W2034146801 citedByCount "21" @default.
- W2034146801 countsByYear W20341468012016 @default.
- W2034146801 crossrefType "journal-article" @default.
- W2034146801 hasAuthorship W2034146801A5001432477 @default.
- W2034146801 hasAuthorship W2034146801A5019802706 @default.
- W2034146801 hasAuthorship W2034146801A5026348330 @default.
- W2034146801 hasAuthorship W2034146801A5028443519 @default.
- W2034146801 hasAuthorship W2034146801A5028883400 @default.
- W2034146801 hasAuthorship W2034146801A5042951664 @default.
- W2034146801 hasAuthorship W2034146801A5080213567 @default.
- W2034146801 hasAuthorship W2034146801A5080630464 @default.
- W2034146801 hasAuthorship W2034146801A5084568832 @default.
- W2034146801 hasConcept C104317684 @default.
- W2034146801 hasConcept C138626823 @default.
- W2034146801 hasConcept C147483822 @default.
- W2034146801 hasConcept C153911025 @default.
- W2034146801 hasConcept C158617107 @default.
- W2034146801 hasConcept C159654299 @default.
- W2034146801 hasConcept C167672396 @default.
- W2034146801 hasConcept C2776396001 @default.
- W2034146801 hasConcept C30481170 @default.
- W2034146801 hasConcept C53226629 @default.
- W2034146801 hasConcept C54355233 @default.
- W2034146801 hasConcept C70278784 @default.
- W2034146801 hasConcept C81885089 @default.
- W2034146801 hasConcept C86803240 @default.
- W2034146801 hasConceptScore W2034146801C104317684 @default.
- W2034146801 hasConceptScore W2034146801C138626823 @default.
- W2034146801 hasConceptScore W2034146801C147483822 @default.
- W2034146801 hasConceptScore W2034146801C153911025 @default.
- W2034146801 hasConceptScore W2034146801C158617107 @default.
- W2034146801 hasConceptScore W2034146801C159654299 @default.
- W2034146801 hasConceptScore W2034146801C167672396 @default.
- W2034146801 hasConceptScore W2034146801C2776396001 @default.
- W2034146801 hasConceptScore W2034146801C30481170 @default.
- W2034146801 hasConceptScore W2034146801C53226629 @default.
- W2034146801 hasConceptScore W2034146801C54355233 @default.
- W2034146801 hasConceptScore W2034146801C70278784 @default.
- W2034146801 hasConceptScore W2034146801C81885089 @default.
- W2034146801 hasConceptScore W2034146801C86803240 @default.
- W2034146801 hasIssue "1" @default.
- W2034146801 hasLocation W20341468011 @default.
- W2034146801 hasLocation W20341468012 @default.
- W2034146801 hasOpenAccess W2034146801 @default.
- W2034146801 hasPrimaryLocation W20341468011 @default.
- W2034146801 hasRelatedWork W1970446973 @default.
- W2034146801 hasRelatedWork W1980356048 @default.