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- W2034148691 abstract "A new mitorubrin congener designated 6′-hydroxy-3′-methoxy-mitorubrin (1) was isolated along with structurally related 4′-hydroxy-3′-methoxy-(S)-mitorubrin (2) and monomethyl-(S)-mitorubrin (3) from the culture broth of Penicillium radicum FKI-3765-2 by solvent extraction, octadecyl silyl (ODS) column chromatography and HPLC. The structure of 1 was elucidated by various spectral analyses, including NMR experiments. They have a common isochromane-like ring with a similar hydrophobic side chain. These compounds moderately potentiated miconazole activity against Candida albicans." @default.
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- W2034148691 date "2010-01-01" @default.
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- W2034148691 title "6'-Hydroxy-3'-methoxy-mitorubrin, a New Potentiator of Antifungal Miconazole Activity, Produced by Penicillium radicum FKI-3765-2" @default.
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- W2034148691 doi "https://doi.org/10.1248/cpb.58.829" @default.
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