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• W2034149357 abstract "An overview is given on the role of progesterone in parturition in the human. Progesterone withdrawal is considered to be a major event for the beginning of parturition. However, in the human, no evidence exists in favour of a decline in placental progesterone production prior to labour. Progesterone actions are mediated by two functionally different but structurally highly related intranuclear proteins, progesterone receptor (PR) A and PRB. In the human, functional progesterone withdrawal is thought to play a role. This may be mediated by a change in the expression of the two isoforms of the PR, with an increase in the PRA:PRB ratio, and this is accompanied by an increase in the expression of the estrogen receptor. These mechanisms are considered to be critical for the endocrine control of parturition." @default.
• W2034149357 created "2016-06-24" @default.
• W2034149357 creator A5024868031 @default.
• W2034149357 date "2005-12-01" @default.
• W2034149357 modified "2023-09-26" @default.
• W2034149357 title "Progesterone receptors in the human uterus and their possible role in parturition" @default.
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• W2034149357 doi "https://doi.org/10.1016/j.jsbmb.2005.08.011" @default.
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