FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034150724> ?p ?o ?g. }

• W2034150724 endingPage "1491" @default.
• W2034150724 startingPage "1481" @default.
• W2034150724 abstract "Proton pump inhibitors can be effective as maintenance therapy in reducing the relapse rate of reflux oesophagitis at a dose lower than that used for acute healing.Patients (n=396, 18-88 years old) with healed reflux oesophagitis (grade II or III before healing) were included in this multinational, prospective, parallel-group, randomized double-blind study. They took oral pantoprazole 20 mg (n=203) or 40 mg (n=193), once daily for up to 12 months. Scheduled endoscopies were performed at entry, after 6 and 12 months, or when symptoms of at least moderate intensity were perceived on 3 consecutive days; symptoms were assessed every 3 months. The primary efficacy parameter was the time until endoscopically proven relapse of reflux oesophagitis occurred; the secondary parameters included tolerability, safety and time until symptomatic relapse occurred.Analysis was performed using the 'all-patients-treated' approach. Endoscopic relapse rates in the 20 mg group after 6 and 12 months were 16 and 29%, respectively; in the 40 mg group, they were 7 and 19%, respectively. Symptomatic relapse rates after 6 and 12 months were 14 and 21% in the 20 mg group and 10 and 17% in the 40 mg group, respectively. Pantoprazole 20 mg and 40 mg were well tolerated throughout the study; the type and frequency of adverse events reported were similar for both treatment groups.The 20 mg dose was proven to be 'at least equivalent' to the 40 mg dose with respect to endoscopic and symptomatic relapse. The 20 mg once daily dose represents an effective and safe maintenance regimen for the majority of patients with healed reflux oesophagitis." @default.
• W2034150724 created "2016-06-24" @default.
• W2034150724 creator A5028058092 @default.
• W2034150724 creator A5040742916 @default.
• W2034150724 creator A5047173159 @default.
• W2034150724 creator A5061950378 @default.
• W2034150724 creator A5066205493 @default.
• W2034150724 creator A5074552098 @default.
• W2034150724 date "1999-11-01" @default.
• W2034150724 modified "2023-09-24" @default.
• W2034150724 title "Maintenance therapy with pantoprazole 20 mg prevents relapse of reflux oesophagitis" @default.
• W2034150724 cites W1967672362 @default.
• W2034150724 cites W1971705529 @default.
• W2034150724 cites W1976099133 @default.
• W2034150724 cites W1985636157 @default.
• W2034150724 cites W1994539467 @default.
• W2034150724 cites W2008339005 @default.
• W2034150724 cites W2008373894 @default.
• W2034150724 cites W2010026303 @default.
• W2034150724 cites W2019233576 @default.
• W2034150724 cites W2032521184 @default.
• W2034150724 cites W2053253142 @default.
• W2034150724 cites W2056726435 @default.
• W2034150724 cites W2061786486 @default.
• W2034150724 cites W2063448572 @default.
• W2034150724 cites W2068778005 @default.
• W2034150724 cites W2075120258 @default.
• W2034150724 cites W2082789523 @default.
• W2034150724 cites W2088829435 @default.
• W2034150724 cites W2089454236 @default.
• W2034150724 cites W2123323260 @default.
• W2034150724 cites W2126528782 @default.
• W2034150724 cites W2126705325 @default.
• W2034150724 cites W2154753708 @default.
• W2034150724 cites W2167293194 @default.
• W2034150724 cites W2170757181 @default.
• W2034150724 cites W2232158329 @default.
• W2034150724 cites W2305357054 @default.
• W2034150724 cites W2313046836 @default.
• W2034150724 doi "https://doi.org/10.1046/j.1365-2036.1999.00651.x" @default.
• W2034150724 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10571605" @default.
• W2034150724 hasPublicationYear "1999" @default.
• W2034150724 type Work @default.
• W2034150724 sameAs 2034150724 @default.
• W2034150724 citedByCount "54" @default.
• W2034150724 countsByYear W20341507242012 @default.
• W2034150724 countsByYear W20341507242014 @default.
• W2034150724 countsByYear W20341507242017 @default.
• W2034150724 countsByYear W20341507242021 @default.
• W2034150724 countsByYear W20341507242023 @default.
• W2034150724 crossrefType "journal-article" @default.
• W2034150724 hasAuthorship W2034150724A5028058092 @default.
• W2034150724 hasAuthorship W2034150724A5040742916 @default.
• W2034150724 hasAuthorship W2034150724A5047173159 @default.
• W2034150724 hasAuthorship W2034150724A5061950378 @default.
• W2034150724 hasAuthorship W2034150724A5066205493 @default.
• W2034150724 hasAuthorship W2034150724A5074552098 @default.
• W2034150724 hasConcept C126322002 @default.
• W2034150724 hasConcept C141071460 @default.
• W2034150724 hasConcept C168563851 @default.
• W2034150724 hasConcept C197934379 @default.
• W2034150724 hasConcept C2777498785 @default.
• W2034150724 hasConcept C2778375690 @default.
• W2034150724 hasConcept C2779134260 @default.
• W2034150724 hasConcept C2779920096 @default.
• W2034150724 hasConcept C2781025758 @default.
• W2034150724 hasConcept C2781315423 @default.
• W2034150724 hasConcept C43270747 @default.
• W2034150724 hasConcept C71924100 @default.
• W2034150724 hasConcept C90924648 @default.
• W2034150724 hasConceptScore W2034150724C126322002 @default.
• W2034150724 hasConceptScore W2034150724C141071460 @default.
• W2034150724 hasConceptScore W2034150724C168563851 @default.
• W2034150724 hasConceptScore W2034150724C197934379 @default.
• W2034150724 hasConceptScore W2034150724C2777498785 @default.
• W2034150724 hasConceptScore W2034150724C2778375690 @default.
• W2034150724 hasConceptScore W2034150724C2779134260 @default.
• W2034150724 hasConceptScore W2034150724C2779920096 @default.
• W2034150724 hasConceptScore W2034150724C2781025758 @default.
• W2034150724 hasConceptScore W2034150724C2781315423 @default.
• W2034150724 hasConceptScore W2034150724C43270747 @default.
• W2034150724 hasConceptScore W2034150724C71924100 @default.
• W2034150724 hasConceptScore W2034150724C90924648 @default.
• W2034150724 hasIssue "11" @default.
• W2034150724 hasLocation W20341507241 @default.
• W2034150724 hasLocation W20341507242 @default.
• W2034150724 hasOpenAccess W2034150724 @default.
• W2034150724 hasPrimaryLocation W20341507241 @default.
• W2034150724 hasRelatedWork W1982494163 @default.
• W2034150724 hasRelatedWork W1983684567 @default.
• W2034150724 hasRelatedWork W2011370817 @default.
• W2034150724 hasRelatedWork W2031772836 @default.
• W2034150724 hasRelatedWork W2054999064 @default.
• W2034150724 hasRelatedWork W2070385619 @default.
• W2034150724 hasRelatedWork W2089617885 @default.
• W2034150724 hasRelatedWork W2159905106 @default.
• W2034150724 hasRelatedWork W4285154846 @default.
• W2034150724 hasRelatedWork W2741043795 @default.

• next