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• W2034153987 abstract "Summary Myasthenia gravis, affecting neuromuscular transmission, leads to a large variability in sensitivity to depolarising and non‐depolarising neuromuscular blocking drugs. We report the successful use of the modified μ‐cyclodextrin sugammadex in a myasthenic patient to reverse a rocuronium‐induced deep level of neuromuscular block. After spontaneous neuromuscular recovery of T2 (second twitch of the train‐of‐four series), we administered 2 mg.kg −1 of sugammadex intravenously, reversing neuromuscular blockade to a train‐of‐four ratio (T4/T1) > 90% within 210 s. Sugammadex, in combination with objective neuromuscular monitoring, can be used to reverse rocuronium‐induced neuromuscular blockade in patients with myasthenia gravis, thereby avoiding the need for reversal with acetylcholinesterase inhibitors." @default.
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• W2034153987 date "2010-02-05" @default.
• W2034153987 modified "2023-10-17" @default.
• W2034153987 title "The use of sugammadex in a patient with myasthenia gravis" @default.
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• W2034153987 doi "https://doi.org/10.1111/j.1365-2044.2009.06236.x" @default.
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