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• W2034155385 abstract "Tissue engineering describes an initiative whereby a deficit of tissue may be replaced with an engineered construct, typically thought to be some combination of a structural support element and a cellular element. There are several mechanical aspects that come into play during the design of such a construct. First, the way in which the mechanical behavior of a tissue is characterized varies depending on the tissue type. For example, one would not consider the ultimate strength of a non-load-bearing tissue such as adipose. However, in bone, where this property helps to describe a functional role, it is of paramount importance. In addition, the arrangement of material chosen to represent the design space has implications regarding the mechanical performance of the scaffold on several different size scales, from the cellular toward the macroscopic. The loading experienced by the implant must also be within the native tissue's mechanical usage window. Future knowledge gained on this subject will continue to characterize the mechanical requirements of various tissues, so that engineering solutions, such as computer-aided tissue engineering, may be utilized from this knowledge. In this article we describe some of these requirements and solutions using bone tissue as an example." @default.
• W2034155385 created "2016-06-24" @default.
• W2034155385 creator A5010965740 @default.
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• W2034155385 date "2005-08-01" @default.
• W2034155385 modified "2023-10-14" @default.
• W2034155385 title "Mechanical Aspects of Tissue Engineering" @default.
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• W2034155385 doi "https://doi.org/10.1055/s-2005-919717" @default.
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