Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034155621> ?p ?o ?g. }
- W2034155621 endingPage "94" @default.
- W2034155621 startingPage "88" @default.
- W2034155621 abstract "Abstract Objective For young subjects, it is well‐documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age‐related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods As an alternative approach to training, we have introduced a tactile coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results By applying coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age‐related impairment of tactile two‐point discrimination can be mitigated substantially. In elderly adults, tactile‐acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50‐year‐old subjects showed intermediate performance. As a result of coactivation, discrimination thresholds of the 80‐year‐old adults came to match those typically found at an age of 50, demonstrating that age‐related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions. Ann Neurol 2006." @default.
- W2034155621 created "2016-06-24" @default.
- W2034155621 creator A5012376803 @default.
- W2034155621 creator A5034938631 @default.
- W2034155621 creator A5043858693 @default.
- W2034155621 creator A5049613382 @default.
- W2034155621 creator A5050145362 @default.
- W2034155621 creator A5072302870 @default.
- W2034155621 date "2006-06-23" @default.
- W2034155621 modified "2023-10-12" @default.
- W2034155621 title "Tactile coactivation resets age-related decline of human tactile discrimination" @default.
- W2034155621 cites W1513406171 @default.
- W2034155621 cites W1782593725 @default.
- W2034155621 cites W1964477575 @default.
- W2034155621 cites W1970944806 @default.
- W2034155621 cites W1971791297 @default.
- W2034155621 cites W1973253631 @default.
- W2034155621 cites W1976817906 @default.
- W2034155621 cites W1976933908 @default.
- W2034155621 cites W1986909933 @default.
- W2034155621 cites W1987571446 @default.
- W2034155621 cites W1995466921 @default.
- W2034155621 cites W2020227161 @default.
- W2034155621 cites W2023831571 @default.
- W2034155621 cites W2036890922 @default.
- W2034155621 cites W2040333128 @default.
- W2034155621 cites W2045005199 @default.
- W2034155621 cites W2048018219 @default.
- W2034155621 cites W2069056384 @default.
- W2034155621 cites W2074235722 @default.
- W2034155621 cites W2075171228 @default.
- W2034155621 cites W2075533164 @default.
- W2034155621 cites W2076359113 @default.
- W2034155621 cites W2091172809 @default.
- W2034155621 cites W2091966751 @default.
- W2034155621 cites W2094396481 @default.
- W2034155621 cites W2098695908 @default.
- W2034155621 cites W2103423395 @default.
- W2034155621 cites W2114749031 @default.
- W2034155621 cites W2118563793 @default.
- W2034155621 cites W2123955652 @default.
- W2034155621 cites W2126587429 @default.
- W2034155621 cites W2129375705 @default.
- W2034155621 cites W2134353679 @default.
- W2034155621 cites W2138629574 @default.
- W2034155621 cites W2159170439 @default.
- W2034155621 cites W270186416 @default.
- W2034155621 doi "https://doi.org/10.1002/ana.20862" @default.
- W2034155621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16685697" @default.
- W2034155621 hasPublicationYear "2006" @default.
- W2034155621 type Work @default.
- W2034155621 sameAs 2034155621 @default.
- W2034155621 citedByCount "115" @default.
- W2034155621 countsByYear W20341556212012 @default.
- W2034155621 countsByYear W20341556212013 @default.
- W2034155621 countsByYear W20341556212014 @default.
- W2034155621 countsByYear W20341556212015 @default.
- W2034155621 countsByYear W20341556212016 @default.
- W2034155621 countsByYear W20341556212017 @default.
- W2034155621 countsByYear W20341556212018 @default.
- W2034155621 countsByYear W20341556212019 @default.
- W2034155621 countsByYear W20341556212020 @default.
- W2034155621 countsByYear W20341556212021 @default.
- W2034155621 countsByYear W20341556212022 @default.
- W2034155621 countsByYear W20341556212023 @default.
- W2034155621 crossrefType "journal-article" @default.
- W2034155621 hasAuthorship W2034155621A5012376803 @default.
- W2034155621 hasAuthorship W2034155621A5034938631 @default.
- W2034155621 hasAuthorship W2034155621A5043858693 @default.
- W2034155621 hasAuthorship W2034155621A5049613382 @default.
- W2034155621 hasAuthorship W2034155621A5050145362 @default.
- W2034155621 hasAuthorship W2034155621A5072302870 @default.
- W2034155621 hasConcept C110235638 @default.
- W2034155621 hasConcept C138496976 @default.
- W2034155621 hasConcept C15744967 @default.
- W2034155621 hasConcept C169760540 @default.
- W2034155621 hasConcept C180747234 @default.
- W2034155621 hasConcept C22033958 @default.
- W2034155621 hasConcept C26760741 @default.
- W2034155621 hasConcept C2777515770 @default.
- W2034155621 hasConcept C2780060146 @default.
- W2034155621 hasConcept C548259974 @default.
- W2034155621 hasConcept C71924100 @default.
- W2034155621 hasConcept C94487597 @default.
- W2034155621 hasConcept C99508421 @default.
- W2034155621 hasConceptScore W2034155621C110235638 @default.
- W2034155621 hasConceptScore W2034155621C138496976 @default.
- W2034155621 hasConceptScore W2034155621C15744967 @default.
- W2034155621 hasConceptScore W2034155621C169760540 @default.
- W2034155621 hasConceptScore W2034155621C180747234 @default.
- W2034155621 hasConceptScore W2034155621C22033958 @default.
- W2034155621 hasConceptScore W2034155621C26760741 @default.
- W2034155621 hasConceptScore W2034155621C2777515770 @default.
- W2034155621 hasConceptScore W2034155621C2780060146 @default.
- W2034155621 hasConceptScore W2034155621C548259974 @default.
- W2034155621 hasConceptScore W2034155621C71924100 @default.
- W2034155621 hasConceptScore W2034155621C94487597 @default.
- W2034155621 hasConceptScore W2034155621C99508421 @default.