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• W2034157619 endingPage "212" @default.
• W2034157619 startingPage "202" @default.
• W2034157619 abstract "ABSTRACT Bacterial genomes with two (or more) chromosome-like replicons are known, and these appear to be particularly frequent in alphaproteobacteria. The genome of the N 2 -fixing alfalfa symbiont Sinorhizobium meliloti 1021 contains a 3.7-Mb chromosome and 1.4-Mb (pSymA) and 1.7-Mb (pSymB) megaplasmids. In this study, the tRNA arg and engA genes, located on the pSymB megaplasmid, are shown to be essential for growth. These genes could be deleted from pSymB when copies were previously integrated into the chromosome. However, in the closely related strain Sinorhizobium fredii NGR234, the tRNA arg and engA genes are located on the chromosome, in a 69-kb region designated the engA- tRNA arg -rmlC region. This region includes bacA , a gene that is important for intracellular survival during host-bacterium interactions for S. meliloti and the related alphaproteobacterium Brucella abortus . The engA- tRNA arg -rmlC region lies between the kdgK and dppF2 (NGR_c24410) genes on the S. fredii chromosome. Synteny analysis showed that kdgK and dppF2 orthologues are adjacent to each other on the chromosomes of 15 sequenced strains of S. meliloti and Sinorhizobium medicae , whereas the 69-kb engA- tRNA arg -rmlC region is present on the pSymB-equivalent megaplasmids. This and other evidence strongly suggests that the engA- tRNA arg -rmlC region translocated from the chromosome to the progenitor of pSymB in an ancestor common to S. meliloti and S. medicae . To our knowledge, this work represents one of the first experimental demonstrations that essential genes are present on a megaplasmid." @default.
• W2034157619 created "2016-06-24" @default.
• W2034157619 creator A5000015314 @default.
• W2034157619 creator A5000810338 @default.
• W2034157619 creator A5020146148 @default.
• W2034157619 creator A5024495861 @default.
• W2034157619 date "2013-01-15" @default.
• W2034157619 modified "2023-10-14" @default.
• W2034157619 title "The tRNA ^arg Gene and <i>engA</i> Are Essential Genes on the 1.7-Mb pSymB Megaplasmid of Sinorhizobium meliloti and Were Translocated Together from the Chromosome in an Ancestral Strain" @default.
• W2034157619 cites W1490899671 @default.
• W2034157619 cites W1493961769 @default.
• W2034157619 cites W1527060445 @default.
• W2034157619 cites W1631101819 @default.
• W2034157619 cites W1664307505 @default.
• W2034157619 cites W1690639239 @default.
• W2034157619 cites W1867281732 @default.
• W2034157619 cites W1880436856 @default.
• W2034157619 cites W1959389742 @default.
• W2034157619 cites W1967164846 @default.
• W2034157619 cites W1977996419 @default.
• W2034157619 cites W1978729112 @default.
• W2034157619 cites W1986245405 @default.
• W2034157619 cites W1986867062 @default.
• W2034157619 cites W1989965961 @default.
• W2034157619 cites W1997329740 @default.
• W2034157619 cites W1999630130 @default.
• W2034157619 cites W2000254253 @default.
• W2034157619 cites W2005101499 @default.
• W2034157619 cites W2006696799 @default.
• W2034157619 cites W2010687343 @default.
• W2034157619 cites W2018255182 @default.
• W2034157619 cites W2019121099 @default.
• W2034157619 cites W2022342560 @default.
• W2034157619 cites W2032995229 @default.
• W2034157619 cites W2038778059 @default.
• W2034157619 cites W2039779035 @default.
• W2034157619 cites W2041257508 @default.
• W2034157619 cites W2043798738 @default.
• W2034157619 cites W2050537059 @default.
• W2034157619 cites W2054275184 @default.
• W2034157619 cites W2059097676 @default.
• W2034157619 cites W2061172567 @default.
• W2034157619 cites W2064815954 @default.
• W2034157619 cites W2073953726 @default.
• W2034157619 cites W2078805723 @default.
• W2034157619 cites W2079070241 @default.
• W2034157619 cites W2081669449 @default.
• W2034157619 cites W2088309661 @default.
• W2034157619 cites W2093312216 @default.
• W2034157619 cites W2100702435 @default.
• W2034157619 cites W2104647883 @default.
• W2034157619 cites W2107109782 @default.
• W2034157619 cites W2111408853 @default.
• W2034157619 cites W2111615135 @default.
• W2034157619 cites W2111771767 @default.
• W2034157619 cites W2114604152 @default.
• W2034157619 cites W2115610944 @default.
• W2034157619 cites W2115736484 @default.
• W2034157619 cites W2118072443 @default.
• W2034157619 cites W2118591257 @default.
• W2034157619 cites W2118608067 @default.
• W2034157619 cites W2121891040 @default.
• W2034157619 cites W2122074279 @default.
• W2034157619 cites W2127975895 @default.
• W2034157619 cites W2129497695 @default.
• W2034157619 cites W2130465193 @default.
• W2034157619 cites W2135061731 @default.
• W2034157619 cites W2135198327 @default.
• W2034157619 cites W2135962145 @default.
• W2034157619 cites W2137015675 @default.
• W2034157619 cites W2143075759 @default.
• W2034157619 cites W2145385227 @default.
• W2034157619 cites W2149184205 @default.
• W2034157619 cites W2150316104 @default.
• W2034157619 cites W2151620364 @default.
• W2034157619 cites W2152253857 @default.
• W2034157619 cites W2153018010 @default.
• W2034157619 cites W2153360620 @default.
• W2034157619 cites W2155066423 @default.
• W2034157619 cites W2155869117 @default.
• W2034157619 cites W2158147022 @default.
• W2034157619 cites W2158153204 @default.
• W2034157619 cites W2158866354 @default.
• W2034157619 cites W2163127726 @default.
• W2034157619 cites W2167198186 @default.
• W2034157619 cites W2169150541 @default.
• W2034157619 cites W2170408878 @default.
• W2034157619 cites W2170692363 @default.
• W2034157619 doi "https://doi.org/10.1128/jb.01758-12" @default.
• W2034157619 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3553834" @default.
• W2034157619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23123907" @default.
• W2034157619 hasPublicationYear "2013" @default.
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