FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034160209> ?p ?o ?g. }

• W2034160209 endingPage "1300" @default.
• W2034160209 startingPage "1295" @default.
• W2034160209 abstract "AT1 receptor antagonists control blood pressure (BP) effectively and reduce left ventricular hypertrophy in patients with essential hypertension. Because left ventricular hypertrophy is very common in renal transplant recipients, we examined the cardiovascular effects and the safety profile of the AT1 receptor antagonist losartan in hypertensive renal transplant recipients. In 20 renal transplant recipients with stable renal graft function 50 mg of losartan was added to the preexisting antihypertensive treatment (no angiotensin-converting enzyme inhibitors) at least 6 months after renal transplantation. Twenty-four-hour ambulatory BP, two-dimensional-guided M-mode echocardiography, and duplex sonography, as well as renal function, red blood cell count, cyclosporine A and FK 506 levels, erythropoetin, and angiotensin II concentration were determined at baseline and after 6 months of therapy. With 24-h ambulatory BP measurement, systolic blood pressure (SBP) was reduced by 7.5 +/- 2.4 mm Hg and diastolic blood pressure (DBP) by 4.5 +/- 1.8 mm Hg (P < .01 and P < .05, respectively). Posterior, septal, and relative wall thickness decreased by 0.95 +/- 0.2 mm, 0.91 +/- 0.2 mm and 0.04 +/- 0.01 mm, respectively (all P < .001). Left ventricular mass index decreased by 18.1 +/- 4.7 g/m2 (P < .01). Ejection fraction and midwall fractional fiber shortening as systolic parameters and the relation of passive-to-active diastolic filling of the left ventricle were unaltered. Serum creatinine and cyclosporine A concentration remained stable in all patients. Hemoglobin and hematocrit decreased by 1.0 +/- 0.3 g/dL and 3.6% +/- 0.9%, respectively (P < .002 and P < .001) without a change in serum erythropoetin level. In renal transplant recipients the AT1 receptor antagonist losartan reduces left ventricular hypertrophy without altering systolic or diastolic function. It is safe with regard to renal function and immunosuppression, but slightly decreases hemoglobin level." @default.
• W2034160209 created "2016-06-24" @default.
• W2034160209 creator A5037214274 @default.
• W2034160209 creator A5040449404 @default.
• W2034160209 creator A5049235067 @default.
• W2034160209 creator A5058591340 @default.
• W2034160209 creator A5068737935 @default.
• W2034160209 date "2000-12-01" @default.
• W2034160209 modified "2023-09-25" @default.
• W2034160209 title "Regression of left ventricular hypertrophy by at1 receptor blockade in renal transplant recipients" @default.
• W2034160209 cites W1882453895 @default.
• W2034160209 cites W1992890029 @default.
• W2034160209 cites W1996698106 @default.
• W2034160209 cites W1997791597 @default.
• W2034160209 cites W1997980688 @default.
• W2034160209 cites W2014919430 @default.
• W2034160209 cites W2017763752 @default.
• W2034160209 cites W2019609718 @default.
• W2034160209 cites W2031971366 @default.
• W2034160209 cites W2039665384 @default.
• W2034160209 cites W2052153481 @default.
• W2034160209 cites W2053126630 @default.
• W2034160209 cites W2054827086 @default.
• W2034160209 cites W2061569406 @default.
• W2034160209 cites W2063498586 @default.
• W2034160209 cites W2065857828 @default.
• W2034160209 cites W2075830379 @default.
• W2034160209 cites W2076177143 @default.
• W2034160209 cites W2093934591 @default.
• W2034160209 cites W2094196886 @default.
• W2034160209 cites W2096073058 @default.
• W2034160209 cites W2123558577 @default.
• W2034160209 cites W2132929297 @default.
• W2034160209 cites W2154483435 @default.
• W2034160209 cites W2163343261 @default.
• W2034160209 cites W37851286 @default.
• W2034160209 cites W4301499751 @default.
• W2034160209 doi "https://doi.org/10.1016/s0895-7061(00)01213-9" @default.
• W2034160209 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11130774" @default.
• W2034160209 hasPublicationYear "2000" @default.
• W2034160209 type Work @default.
• W2034160209 sameAs 2034160209 @default.
• W2034160209 citedByCount "16" @default.
• W2034160209 countsByYear W20341602092013 @default.
• W2034160209 countsByYear W20341602092016 @default.
• W2034160209 countsByYear W20341602092020 @default.
• W2034160209 crossrefType "journal-article" @default.
• W2034160209 hasAuthorship W2034160209A5037214274 @default.
• W2034160209 hasAuthorship W2034160209A5040449404 @default.
• W2034160209 hasAuthorship W2034160209A5049235067 @default.
• W2034160209 hasAuthorship W2034160209A5058591340 @default.
• W2034160209 hasAuthorship W2034160209A5068737935 @default.
• W2034160209 hasBestOaLocation W20341602091 @default.
• W2034160209 hasConcept C126322002 @default.
• W2034160209 hasConcept C134018914 @default.
• W2034160209 hasConcept C149323552 @default.
• W2034160209 hasConcept C159641895 @default.
• W2034160209 hasConcept C164705383 @default.
• W2034160209 hasConcept C2776002628 @default.
• W2034160209 hasConcept C2777097880 @default.
• W2034160209 hasConcept C2778198053 @default.
• W2034160209 hasConcept C2780288358 @default.
• W2034160209 hasConcept C2908929049 @default.
• W2034160209 hasConcept C2911091166 @default.
• W2034160209 hasConcept C71924100 @default.
• W2034160209 hasConcept C78085059 @default.
• W2034160209 hasConcept C84393581 @default.
• W2034160209 hasConceptScore W2034160209C126322002 @default.
• W2034160209 hasConceptScore W2034160209C134018914 @default.
• W2034160209 hasConceptScore W2034160209C149323552 @default.
• W2034160209 hasConceptScore W2034160209C159641895 @default.
• W2034160209 hasConceptScore W2034160209C164705383 @default.
• W2034160209 hasConceptScore W2034160209C2776002628 @default.
• W2034160209 hasConceptScore W2034160209C2777097880 @default.
• W2034160209 hasConceptScore W2034160209C2778198053 @default.
• W2034160209 hasConceptScore W2034160209C2780288358 @default.
• W2034160209 hasConceptScore W2034160209C2908929049 @default.
• W2034160209 hasConceptScore W2034160209C2911091166 @default.
• W2034160209 hasConceptScore W2034160209C71924100 @default.
• W2034160209 hasConceptScore W2034160209C78085059 @default.
• W2034160209 hasConceptScore W2034160209C84393581 @default.
• W2034160209 hasIssue "12" @default.
• W2034160209 hasLocation W20341602091 @default.
• W2034160209 hasLocation W20341602092 @default.
• W2034160209 hasOpenAccess W2034160209 @default.
• W2034160209 hasPrimaryLocation W20341602091 @default.
• W2034160209 hasRelatedWork W2027470168 @default.
• W2034160209 hasRelatedWork W2101909726 @default.
• W2034160209 hasRelatedWork W2371035309 @default.
• W2034160209 hasRelatedWork W2372955497 @default.
• W2034160209 hasRelatedWork W2376516711 @default.
• W2034160209 hasRelatedWork W2377127652 @default.
• W2034160209 hasRelatedWork W2377476789 @default.
• W2034160209 hasRelatedWork W2383836865 @default.
• W2034160209 hasRelatedWork W2392747730 @default.
• W2034160209 hasRelatedWork W3029079747 @default.
• W2034160209 hasVolume "13" @default.
• W2034160209 isParatext "false" @default.

• next